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MULTISPECIES: DNA-binding transcriptional repressor LacI


LOCUS       WP_000805902             360 aa            linear   BCT 26-FEB-2020
            [Bacteria][Archaea].
ACCESSION   WP_000805902
VERSION     WP_000805902.1
KEYWORDS    RefSeq; CROSS_KINGDOM.
SOURCE      Bacteria (eubacteria)
  ORGANISM  Bacteria
            Unclassified.
SOURCE      Archaea
  ORGANISM  Archaea
            Unclassified.
REFERENCE   1  (residues 1 to 360)
  AUTHORS   Lewis,M., Chang,G., Horton,N.C., Kercher,M.A., Pace,H.C.,
            Schumacher,M.A., Brennan,R.G. and Lu,P.
  TITLE     Crystal structure of the lactose operon repressor and its complexes
            with DNA and inducer
  JOURNAL   Science 271 (5253), 1247-1254 (1996)
   PUBMED   8638105
REFERENCE   2  (residues 1 to 360)
  AUTHORS   Lehming,N., Sartorius,J., Niemoller,M., Genenger,G., v
            Wilcken-Bergmann,B. and Muller-Hill,B.
  TITLE     The interaction of the recognition helix of lac repressor with lac
            operator
  JOURNAL   EMBO J. 6 (10), 3145-3153 (1987)
   PUBMED   2826131
REFERENCE   3  (residues 1 to 360)
  AUTHORS   Riggs,A.D., Suzuki,H. and Bourgeois,S.
  TITLE     Lac repressor-operator interaction. I. Equilibrium studies
  JOURNAL   J. Mol. Biol. 48 (1), 67-83 (1970)
   PUBMED   4915295
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011233
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..360
                     /organism="Bacteria"
                     /db_xref="taxon:2"
     source          1..360
                     /organism="Archaea"
                     /db_xref="taxon:2157"
     gene            1..360
                     /gene="lacI"
     Protein         1..360
                     /product="DNA-binding transcriptional repressor LacI"
                     /calculated_mol_wt=38459
     Region          1..340
                     /region_name="lacI"
                     /note="lac repressor; Reviewed; PRK09526"
                     /db_xref="CDD:181929"
ORIGIN      
        1 mkpvtlydva eyagvsyqtv srvvnqashv saktrekvea amaelnyipn rvaqqlagkq
       61 slligvatss lalhapsqiv aaiksradql gasvvvsmve rsgveackaa vhnllaqrvs
      121 gliinypldd qdaiaveaac tnvpalfldv sdqtpinsii fshedgtrlg vehlvalghq
      181 qiallagpls svsarlrlag whkyltrnqi qpiaeregdw samsgfqqtm qmlnegivpt
      241 amlvandqma lgamraites glrvgadisv vgyddtedss cyipplttik qdfrllgqts
      301 vdrllqlsqg qavkgnqllp vslvkrkttl apntqtaspr aladslmqla rqvsrlesgq