3-methyl-2-oxobutanoate hydroxymethyltransferase [Escherichia

LOCUS       WP_000805473             264 aa            linear   BCT 03-JUN-2019
            coli].
ACCESSION   WP_000805473
VERSION     WP_000805473.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 264)
  AUTHORS   Jones,C.E., Brook,J.M., Buck,D., Abell,C. and Smith,A.G.
  TITLE     Cloning and sequencing of the Escherichia coli panB gene, which
            encodes ketopantoate hydroxymethyltransferase, and overexpression
            of the enzyme
  JOURNAL   J. Bacteriol. 175 (7), 2125-2130 (1993)
   PUBMED   8096212
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00222.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..264
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..264
                     /gene="panB"
     Protein         1..264
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /EC_number="2.1.2.11"
                     /GO_function="GO:0003864 - 3-methyl-2-oxobutanoate
                     hydroxymethyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=28179
     Region          4..262
                     /region_name="PanB"
                     /note="Ketopantoate hydroxymethyltransferase [Coenzyme
                     transport and metabolism]; COG0413"
                     /db_xref="CDD:440182"
ORIGIN      
        1 mkpttiaslq kckqekkrfa titaydysfa klfaeeglnv mlvgdslgmt vqghestlpv
       61 tvediayhtt avrrgapncl lladlpfmay atpeqafena atvmraganm vkieggewlv
      121 etvkmltera vpvcghlglt pqsvnifggy kvqgrgdeas drllsdalal eaagaqllvl
      181 ecvpvelakr itealaipvi gigagnvtdg qilvmhdafg itgghipkfa knflaetgdi
      241 raavrqymae vesgvypgee hsfh