MULTISPECIES: glyoxylate/hydroxypyruvate reductase GhrB

LOCUS       WP_000805027             324 aa            linear   BCT 31-MAY-2019
            [Enterobacteriaceae].
ACCESSION   WP_000805027
VERSION     WP_000805027.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF011938.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK15409
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..324
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..324
                     /gene="ghrB"
     Protein         1..324
                     /product="glyoxylate/hydroxypyruvate reductase GhrB"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /calculated_mol_wt=35265
     Region          1..323
                     /region_name="PRK15409"
                     /note="glyoxylate/hydroxypyruvate reductase GhrB"
                     /db_xref="CDD:185307"
     Site            order(9..10,12,52,53,73,101..102,105..106,108..109,112,
                     116,118,126,128,130,133..139,140..144,162..163,167..168,
                     266..267,275,281..287,289..292,294)
                     /site_type="other"
                     /note="dimerization interface [polypeptide binding]"
                     /db_xref="CDD:240626"
     Site            order(74..76,99,237,285,288)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:240626"
     Site            order(75..76,103,152..156,175..177,180,207..209,213..214,
                     235..237,261..262,285,287..288)
                     /site_type="other"
                     /note="NADP binding site [chemical binding]"
                     /db_xref="CDD:240626"
ORIGIN      
        1 mkpsvilyka lpddllqrlq ehftvhqvan lspqtveqna aifaeaegll gsnenvdaal
       61 lekmpklrat stisvgydnf dvdaltarki llmhtptvlt etvadtlmal vlstarrvve
      121 vaervkagew tasigpdwyg tdvhhktlgi vgmgrigmal aqrahfgfnm pilynarrhh
      181 keaeerfnar ycdldtllqe sdfvclilpl tdethhlfga eqfakmkssa ifinagrgpv
      241 vdenaliaal qkgeihaagl dvfeqeplsv dspllsmanv vavphigsat hetrygmaac
      301 avdnlidalq gkvekncvnp hvad