MULTISPECIES: glyoxylate/hydroxypyruvate reductase GhrB [Shigella].

LOCUS       WP_000804996             324 aa            linear   BCT 17-NOV-2023
ACCESSION   WP_000804996
VERSION     WP_000804996.1
KEYWORDS    RefSeq.
SOURCE      Shigella
  ORGANISM  Shigella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF011938.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK15409
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..324
                     /organism="Shigella"
                     /db_xref="taxon:620"
     gene            1..324
                     /gene="ghrB"
     Protein         1..324
                     /product="glyoxylate/hydroxypyruvate reductase GhrB"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /calculated_mol_wt=35206
     Region          1..323
                     /region_name="PRK15409"
                     /note="glyoxylate/hydroxypyruvate reductase GhrB"
                     /db_xref="CDD:185307"
     Site            order(9..10,12,52,53,73,101..102,105..106,108..109,112,
                     116,118,126,128,130,133..139,140..144,162..163,167..168,
                     266..267,275,281..287,289..292,294)
                     /site_type="other"
                     /note="dimerization interface [polypeptide binding]"
                     /db_xref="CDD:240626"
     Site            order(74..76,99,237,285,288)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:240626"
     Site            order(75..76,103,152..156,175..177,180,207..209,213..214,
                     235..237,261..262,285,287..288)
                     /site_type="other"
                     /note="NADP binding site [chemical binding]"
                     /db_xref="CDD:240626"
ORIGIN      
        1 mkpsvilyka lpddllqrlq ahftvhqvan lspqtvvqna aifaeaegll gsnenvdaal
       61 lekmpklrat stisvgydnf dvdaltarki llmhtptvlt etvadtlmal vlstarrvve
      121 vaervkagew tasigpdwyg tdvhhktlgi vgmgrigmal aqrvhfgfnm pilynarrhh
      181 keaeerfnar ycdldtllqe sdfvclilpl tdethhlfga eqfakmkssa ifinagrgpv
      241 vdenaliaal qkgeihaagl dvfeqeplsv dspllsmanv vavphigsat hetrygmaac
      301 avdnlidalq gkvekncvnp hvad