NAD(P)-dependent alcohol dehydrogenase [Escherichia coli].

LOCUS       WP_000798125             347 aa            linear   BCT 12-JUL-2017
ACCESSION   WP_000798125
VERSION     WP_000798125.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10143035
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..347
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /calculated_mol_wt=37556
     Region          6..345
                     /region_name="sorbitol_DH"
                     /note="Sorbitol dehydrogenase; cd05285"
                     /db_xref="CDD:176188"
     Site            order(39,41,45,51,54,65,114,117,152,269,291..292)
                     /site_type="active"
                     /note="inhibitor binding site [active]"
                     /db_xref="CDD:176188"
     Site            order(39,41,65..66,152)
                     /site_type="other"
                     /note="catalytic Zn binding site [ion binding]"
                     /db_xref="CDD:176188"
     Site            order(95,98,101,109)
                     /site_type="other"
                     /note="structural Zn binding site [ion binding]"
                     /db_xref="CDD:176188"
     Site            order(156,178..180,199..201,205,220,244..245,247,267..269,
                     290..292)
                     /site_type="other"
                     /note="NADP binding site [chemical binding]"
                     /db_xref="CDD:176188"
     Site            order(158,169,171,187,190..192,194,203,219,231,299,
                     302..303,306)
                     /site_type="other"
                     /note="tetramer interface [polypeptide binding]"
                     /db_xref="CDD:176188"
ORIGIN      
        1 mknskailqv pgtmkiisae ipvpkedevl ikveyvgicg sdvhgfesgp fippkdpnqe
       61 iglghecagt vvavgsrvrk fkpgdrvnie pgvpcghcry clegkynicp dvdfmatqpn
      121 yrgalthylc hpesftyklp dnmdtmegtl vepaavgmha amladvkpgk kiiilgagci
      181 glmtlqackc lgateiavvd vlekrlamae qlgatvving akedtiarcq qftedmgadi
      241 vfetagsavt vkqapylvmr ggkimivgtv pgasainflk inrevtiqtv fryanrypvt
      301 ieaissgrfd vksmvthiyd yrdvqqafee svnnkrdiik gvikisd