Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: MFS transporter [Salmonella].


LOCUS       WP_000797678             403 aa            linear   BCT 28-MAR-2023
ACCESSION   WP_000797678
VERSION     WP_000797678.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 403)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 403)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
REFERENCE   3  (residues 1 to 403)
  AUTHORS   Yan,N.
  TITLE     Structural advances for the major facilitator superfamily (MFS)
            transporters
  JOURNAL   Trends Biochem Sci 38 (3), 151-159 (2013)
   PUBMED   23403214
REFERENCE   4  (residues 1 to 403)
  AUTHORS   Law,C.J., Maloney,P.C. and Wang,D.N.
  TITLE     Ins and outs of major facilitator superfamily antiporters
  JOURNAL   Annu Rev Microbiol 62, 289-305 (2008)
   PUBMED   18537473
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13024447
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..403
                     /product="MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=44128
     Region          8..390
                     /region_name="MFS_YdiM_like"
                     /note="Inner membrane transport protein YdiM and similar
                     proteins of the Major Facilitator Superfamily of
                     transporters; cd17396"
                     /db_xref="CDD:340954"
     Site            order(19..20,23..24,27,59,109..110,112..114,117,136,
                     139..140,143,215,218..219,222..224,227,258,262,313..314,
                     318,322,338,341..342,345..346,349)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340954"
ORIGIN      
        1 mknryfptav glyfnyfvhg mgvilmslnm ssleqqwhts aagvsiviss lgigrlsvll
       61 iagmlsdrfg rrpfiilgtt cyliffigil yaqtifvaya cgflagmans fldagtypsl
      121 meafprspst anilikafvs ggqfllpiii sllvwanmwf gwsfllagai mlinalfllr
      181 cpfppypgri lkpkisqapv tgvhhcslid lisytlygyi smatfylisq wlaqygqfva
      241 gmsytqsikl lsiytcgsll cvfitaplvr ktirsttllm fytfisfial ltvclhpqty
      301 ivmifafvig fssaggvvqi gltlmasrfp qekgkatgiy ysagsiatft iplitarise
      361 msiahimwfd tgiaavgfll alfigyrsra esqhhaeaas taq