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MULTISPECIES: bifunctional tetrahydrofolate synthase/dihydrofolate


LOCUS       WP_000792275             422 aa            linear   BCT 19-JUN-2019
            synthase [Salmonella].
ACCESSION   WP_000792275
VERSION     WP_000792275.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008101.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10846
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..422
                     /gene="folC"
     Protein         1..422
                     /product="bifunctional tetrahydrofolate
                     synthase/dihydrofolate synthase"
                     /EC_number="6.3.2.12"
                     /EC_number="6.3.2.17"
                     /GO_function="GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /GO_process="GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /calculated_mol_wt=45350
     Region          1..416
                     /region_name="PRK10846"
                     /note="bifunctional folylpolyglutamate synthase/
                     dihydrofolate synthase; Provisional"
                     /db_xref="CDD:182774"
ORIGIN      
        1 mknksipqaa splaswlsyl enlhsksidl glervsqvaa rldilkpapf vftvagtngk
       61 gttcrtlesv liaagyrvgv yssphlvryt ervrvqgkel aesahtasfa eieaargdis
      121 ltyfeygtls alwlfkqanl dvvilevglg grldatnivd advavitsia ldhtdwlgpd
      181 resigrekag ifraekpaiv gepempatia dvaqetgall rrrgvdwrye vtathwaftd
      241 gdgtlaglpl pqvpqpnaat alaalrasrl nideqairdg iaqatlpgrf qivsesprvi
      301 fdvahnphaa eyltgrlkml pkrgrvlavi gmlhdkdiag tlawlksvvd dwycaplegp
      361 rgataeqlle hlgkgnvyds vaqawqaaid aaqpedtvlv cgsfhtvahv mevidagrig
      421 ge