MULTISPECIES: D-threonate kinase [Salmonella].

LOCUS       WP_000782192             423 aa            linear   BCT 26-NOV-2024
ACCESSION   WP_000782192
VERSION     WP_000782192.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 423)
  AUTHORS   Thiaville,J.J., Flood,J., Yurgel,S., Prunetti,L.,
            Elbadawi-Sidhu,M., Hutinet,G., Forouhar,F., Zhang,X., Ganesan,V.,
            Reddy,P., Fiehn,O., Gerlt,J.A., Hunt,J.F., Copley,S.D. and de
            Crecy-Lagard,V.
  TITLE     Members of a Novel Kinase Family (DUF1537) Can Recycle Toxic
            Intermediates into an Essential Metabolite
  JOURNAL   ACS Chem Biol 11 (8), 2304-2311 (2016)
   PUBMED   27294475
REFERENCE   2  (residues 1 to 423)
  AUTHORS   Zhang,X., Carter,M.S., Vetting,M.W., San Francisco,B., Zhao,S.,
            Al-Obaidi,N.F., Solbiati,J.O., Thiaville,J.J., de Crecy-Lagard,V.,
            Jacobson,M.P., Almo,S.C. and Gerlt,J.A.
  TITLE     Assignment of function to a domain of unknown function: DUF1537 is
            a new kinase family in catabolic pathways for acid sugars
  JOURNAL   Proc Natl Acad Sci U S A 113 (29), E4161-E4169 (2016)
   PUBMED   27402745
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF047819.1
            Evidence Source    :: NCBIFAM
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..423
                     /gene="dtnK"
     Protein         1..423
                     /product="D-threonate kinase"
                     /EC_number="2.7.1.219"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /calculated_mol_wt=44855
     Region          2..419
                     /region_name="OtnK"
                     /note="D-threonate/D-erythronate kinase OtnK and related
                     C4-acid sugar kinases, YgbK/DUF1537 family [Carbohydrate
                     transport and metabolism]; COG3395"
                     /db_xref="CDD:442622"
ORIGIN      
        1 mkmiviaddf tgsndtgvql akkgartevm lsasqkpsrr advlvintes rampadqaas
       61 avyaalspwc etspaplvyk kidstfrgni gaevtaamra sqrklaviaa aipaagrttl
      121 egkclvngvp lletefasdp ktpivssria eivalqseip vyevflqdvr rgglsallta
      181 yaaegegiiv vdaveerdlt liaqaaceqp smpllvgaag lanalpvelf mqdrqrlpvl
      241 vvagsmseat rrqvdnalcr graevvdida armvsdsaeq eiasvveqac allsqhrhti
      301 lrtsrraedr qlidalceks amsrqqlger lsqrlgvvtl niieqarigg lfltggdiat
      361 avagalgaeg yriqsevapc ipcgtfvnse iddlpvitka ggfgsdstlc dalyyieemy
      421 cgd