MULTISPECIES: threonine synthase [Enterobacteriaceae].

LOCUS       WP_000781074             428 aa            linear   BCT 08-JUN-2021
ACCESSION   WP_000781074
VERSION     WP_000781074.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 428)
  AUTHORS   Parsot,C.
  TITLE     Evolution of biosynthetic pathways: a common ancestor for threonine
            synthase, threonine dehydratase and D-serine dehydratase
  JOURNAL   EMBO J 5 (11), 3013-3019 (1986)
   PUBMED   3098560
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00260.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..428
                     /gene="thrC"
     Protein         1..428
                     /product="threonine synthase"
                     /EC_number="4.2.3.1"
                     /GO_function="GO:0004795 - threonine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=46983
     Region          2..423
                     /region_name="Thr-synth_2"
                     /note="Threonine synthase catalyzes the final step of
                     threonine biosynthesis. The conversion of
                     O-phosphohomoserine into threonine and inorganic phosphate
                     is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD
                     includes members from higher plants, cyanobacteria;
                     cd01560"
                     /db_xref="CDD:107203"
     Site            order(107,248..249,376)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:107203"
     Site            107
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:107203"
ORIGIN      
        1 mklynlkdhn eqvsfaqavt qglgknqglf fphdlpefsl teidemlkld fvtrsakils
       61 afigdeipqe ileervraaf afpapvanve sdvgclelfh gptlafkdfg grfmaqmlth
      121 iagdkpvtil tatsgdtgaa vahafyglpn vkvvilyprg kisplqeklf ctlggnietv
      181 aidgdfdacq alvkqafdde elkvalglns ansinisrll aqicyyfeav aqlpqetrnq
      241 lvvsvpsgnf gdltagllak slglpvkrfi aatnvndtvp rflhdgqwsp katqatlsna
      301 mdvsqpnnwp rveelfrrki wqlkelgyaa vddettqqtm relkelgyts ephaavayra
      361 lrdqlnpgey glflgtahpa kfkesveail getldlpkel aeradlplls hnlpadfaal
      421 rklmmnhq