class 1b ribonucleoside-diphosphate reductase subunit beta

LOCUS       WP_000777971             319 aa            linear   BCT 17-JUN-2024
            [Escherichia coli].
ACCESSION   WP_000777971
VERSION     WP_000777971.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 319)
  AUTHORS   Zhang,Y. and Stubbe,J.
  TITLE     Bacillus subtilis class Ib ribonucleotide reductase is a
            dimanganese(III)-tyrosyl radical enzyme
  JOURNAL   Biochemistry 50 (25), 5615-5623 (2011)
   PUBMED   21561096
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR04171.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..319
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..319
                     /gene="nrdF"
     Protein         1..319
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=36360
     Region          6..319
                     /region_name="RNR_1b_NrdF"
                     /note="ribonucleoside-diphosphate reductase, class 1b,
                     beta subunit; TIGR04171"
                     /db_xref="CDD:275027"
     Site            order(9,20,27,92..93,96,99..100,103,106,122..123,126)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:153108"
     Site            order(31,67,98,101,105,190..191,195)
                     /site_type="active"
                     /note="putative radical transfer pathway [active]"
                     /db_xref="CDD:153108"
     Site            order(67,98,101,158,192,195)
                     /site_type="other"
                     /note="diiron center [ion binding]"
                     /db_xref="CDD:153108"
     Site            105
                     /site_type="other"
                     /note="tyrosyl radical"
                     /db_xref="CDD:153108"
ORIGIN      
        1 mklsrisain wnkisddkdl evwnrltsnf wlpekvplsn dipawqtltv veqqltmrvf
       61 tgltlldtlq nvigapslmp daltpheeav lsnisfmeav harsyssifs tlcqtkdvda
      121 ayawseenap lqrkaqiiqq hyrgddplkk kiasvflesf lfysgfwlpm yfssrgkltn
      181 tadlirliir deavhgyyig ykyqknmeki slgqreelks fafdlllely dnelqytdel
      241 yaetpwaddv kaflcynank almnlgyepl fpaemaevnp ailaalspna denhdffsgs
      301 gssyvmgkav eteyedwnf