MULTISPECIES: MFS transporter [Salmonella].

LOCUS       WP_000777317             444 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_000777317
VERSION     WP_000777317.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 444)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 444)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 444)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
REFERENCE   4  (residues 1 to 444)
  AUTHORS   Yan,N.
  TITLE     Structural advances for the major facilitator superfamily (MFS)
            transporters
  JOURNAL   Trends Biochem Sci 38 (3), 151-159 (2013)
   PUBMED   23403214
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11454559
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..444
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=49549
     Region          1..444
                     /region_name="MelB"
                     /note="Na+/melibiose symporter or related transporter
                     [Carbohydrate transport and metabolism]; COG2211"
                     /db_xref="CDD:441813"
ORIGIN      
        1 mklsivekig fgagdmainv viiamqllla yfytdiygls aadvgvlfvv vrmidaiidp
       61 amgvltdkln trwgryrpwl lwfaipfgfa vylmfitpdm aymaklaway gtyilmtlvy
      121 taitipyism igvitsdpve rlsangyrfv mtkiaaflvt ivvpmlavwl gqgnkalgyq
      181 fsmglmgamg allfifcflt trersepeit slsvgkqfky llrndqwiil gvvilllmcg
      241 yvirgsvaay yakyylnggd slispflttg vvasilamia ttwitkfwdk ikmfrytqii
      301 tfilsalmyf svgrenlvla fafyflinff cdmqmpvfws siaeavdyge kktglrvsgl
      361 afggilffqk fgmgiaggil gfllshfgyq adveqsarsl tgialmmtli palfhlavgl
      421 lmkkylinne yyrdiqlala qkqa