type II Zorya anti-phage system protein ZorE [Escherichia coli].

LOCUS       WP_000777275             367 aa            linear   BCT 19-JUN-2023
ACCESSION   WP_000777275
VERSION     WP_000777275.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 367)
  AUTHORS   Doron,S., Melamed,S., Ofir,G., Leavitt,A., Lopatina,A., Keren,M.,
            Amitai,G. and Sorek,R.
  TITLE     Systematic discovery of antiphage defense systems in the microbial
            pangenome
  JOURNAL   Science 359 (6379) (2018)
   PUBMED   29371424
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF041791.1
            Evidence Source    :: NCBIFAM
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..367
                     /gene="zorE"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
     Protein         1..367
                     /product="type II Zorya anti-phage system protein ZorE"
                     /GO_process="GO:0051607 - defense response to virus
                     [Evidence IEA]"
                     /calculated_mol_wt=41905
     Region          193..249
                     /region_name="McrA"
                     /note="5-methylcytosine-specific restriction endonuclease
                     McrA [Defense mechanisms]; COG1403"
                     /db_xref="CDD:441013"
ORIGIN      
        1 mklsidisel iqlgkkmlpe gvdffldesp idfdpidiel stgkevsied ldpgsglisy
       61 hgrqvllyir dhsgrydaai vdgekgkrfh iawcrtldem rhknrferyh atnridglfe
      121 iddgsgrsqd vdlrvcmncl erlnykgsid kqrkreifks fslneffsdy stcfrhmpkg
      181 iydktnsgyv enwkeiskei rekanyvcnd cgvnlstakn lchvhhkngi kydnhhenll
      241 vlckdchrkq plhegifvtq aemaiiqrlr sqqgllkaes wneiydltdp svhgdinmmq
      301 hkgfqppvpg ldlpnsehei iatveaawpg lkiavnltpa evegwriytv gelvkeiqtg
      361 aftpakl