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MULTISPECIES: 3-hexulose-6-phosphate synthase [Salmonella].


LOCUS       WP_000776032             211 aa            linear   BCT 02-JUN-2024
ACCESSION   WP_000776032
VERSION     WP_000776032.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 211)
  AUTHORS   Yurimoto,H., Hirai,R., Matsuno,N., Yasueda,H., Kato,N. and Sakai,Y.
  TITLE     HxlR, a member of the DUF24 protein family, is a DNA-binding
            protein that acts as a positive regulator of the
            formaldehyde-inducible hxlAB operon in Bacillus subtilis
  JOURNAL   Mol Microbiol 57 (2), 511-519 (2005)
   PUBMED   15978081
REFERENCE   2  (residues 1 to 211)
  AUTHORS   Wise,E.L., Yew,W.S., Akana,J., Gerlt,J.A. and Rayment,I.
  TITLE     Evolution of enzymatic activities in the orotidine 5'-monophosphate
            decarboxylase suprafamily: structural basis for catalytic
            promiscuity in wild-type and designed mutants of 3-keto-L-gulonate
            6-phosphate decarboxylase
  JOURNAL   Biochemistry 44 (6), 1816-1823 (2005)
   PUBMED   15697207
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR03128.2
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..211
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..211
                     /gene="hxlA"
     Protein         1..211
                     /product="3-hexulose-6-phosphate synthase"
                     /EC_number="4.1.2.43"
                     /GO_function="GO:0043801 - hexulose-6-phosphate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0019647 - formaldehyde assimilation via
                     ribulose monophosphate cycle [Evidence IEA]"
                     /calculated_mol_wt=22585
     Region          2..207
                     /region_name="RuMP_HxlA"
                     /note="3-hexulose-6-phosphate synthase; TIGR03128"
                     /db_xref="CDD:132172"
     Site            order(6,8,30,59,61,134,165,167,187..188)
                     /site_type="active"
                     /db_xref="CDD:240077"
     Site            order(10,37,40..41,64..66,72,86,91,112,119,134,136..138)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:240077"
     Site            order(30,59)
                     /site_type="other"
                     /note="magnesium binding site [ion binding]"
                     /db_xref="CDD:240077"
ORIGIN      
        1 mklqlaldel tlpeamvfmd kvvddvdiie vgtpflireg vnaikaikek yphkevlada
       61 kimdgghfes qllfdagady vtvlgvtdvl tiqsciraak eagkqvvvdm icvddlparv
      121 rlleeagadm lavhtgtdqq aagrkpiddl itmlkvrrka riavaggiss qtvkdyallg
      181 pdvvivgsai thaadpagea rkisqvllqh h