MULTISPECIES: glycine betaine/L-proline ABC transporter permease

LOCUS       WP_000775022             354 aa            linear   BCT 17-JUL-2023
            ProW [Salmonella].
ACCESSION   WP_000775022
VERSION     WP_000775022.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 354)
  AUTHORS   Wang,S., Fang,Y., Wang,Z., Zhang,S., Wang,L., Guo,Y. and Wang,X.
  TITLE     Improving L-threonine production in Escherichia coli by elimination
            of transporters ProP and ProVWX
  JOURNAL   Microb Cell Fact 20 (1), 58 (2021)
   PUBMED   33653345
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 354)
  AUTHORS   Stirling,D.A., Hulton,C.S., Waddell,L., Park,S.F., Stewart,G.S.,
            Booth,I.R. and Higgins,C.F.
  TITLE     Molecular characterization of the proU loci of Salmonella
            typhimurium and Escherichia coli encoding osmoregulated glycine
            betaine transport systems
  JOURNAL   Mol Microbiol 3 (8), 1025-1038 (1989)
   PUBMED   2691838
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008196.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10952
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..354
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..354
                     /gene="proW"
     Protein         1..354
                     /product="glycine betaine/L-proline ABC transporter
                     permease ProW"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=37524
     Region          1..354
                     /region_name="PRK10952"
                     /note="proline/glycine betaine ABC transporter permease
                     ProW"
                     /db_xref="CDD:236805"
     Site            order(161..162,165..166,171,180..183,185..194,197..198,
                     200,216..217,219,221,224..225,227,231..232,235,252,
                     266..267,270,277..280,283..284,297..298,308..309,312..313,
                     315..316,319..320)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:119394"
     Site            order(186..200,277..282)
                     /site_type="active"
                     /note="conserved gate region [active]"
                     /db_xref="CDD:119394"
     Site            order(200,211,283,295,298,308)
                     /site_type="active"
                     /note="putative PBP binding loops [active]"
                     /db_xref="CDD:119394"
     Site            order(236..248,254..255,259)
                     /site_type="active"
                     /note="ABC-ATPase subunit interface [active]"
                     /db_xref="CDD:119394"
ORIGIN      
        1 madqtnpwdt aqvadtttqt adawgtpagv atdggstdwl nsapapapeh fslldpfhkt
       61 lipldswvte gidwvvthfr plfqgirvpv dyilngfqql llgmpapvai ilfaliawqv
      121 sgvgmgiatl isliaigaig awsqamitla lvltallfcv viglpmgiwl arspraakiv
      181 rplldamqtt pafvylvpiv mlfgignvpg vvvtiifalp pivrltilgi nqvpadliea
      241 srsfgasprq mlfkvqlpla mptimagvnq tlmlalsmvv iasmiavggl gqmvlrgigr
      301 ldmglatvgg vgivilaiil drltqavgrd srsrgnrrwy ttgpvglitr pfvk