3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase [Escherichia

LOCUS       WP_000774161             291 aa            linear   BCT 31-MAY-2019
            coli].
ACCESSION   WP_000774161
VERSION     WP_000774161.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF006081.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK08227
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..291
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..291
                     /gene="lsrF"
     Protein         1..291
                     /product="3-hydroxy-5-phosphonooxypentane-2,4-dione
                     thiolase"
                     /EC_number="2.3.1.245"
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /calculated_mol_wt=31764
     Region          28..291
                     /region_name="PRK08227"
                     /note="3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase"
                     /db_xref="CDD:181306"
     Site            order(217,220,241..243,263..265)
                     /site_type="other"
                     /note="putative active site"
                     /db_xref="CDD:188645"
     Site            217
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:188645"
ORIGIN      
        1 madlddikdg kdfrtdqpqk nipftlkgcg aldwgmqsrl srifnpktgk tvmlafdhgy
       61 fqgpttgler idiniaplfe hadvlmctrg ilrsvvppat nkpvvlrasg ansilaelsn
      121 eavalsmdda vrlnscavaa qvyigseyeh qsikniiqlv dagmkvgmpt mavtgvgkdm
      181 vrdqryfsla triaaemgtq iiktyyvekg ferivagcpv piviaggkkl perealemcw
      241 qaidqgasgv dmgrnifqsd hpvammkavq avvhhnetad rayelylsek q