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MULTISPECIES: type II toxin-antitoxin system mRNA interferase toxin


LOCUS       WP_000767829              84 aa            linear   BCT 19-JAN-2021
            YoeB [Enterobacteriaceae].
ACCESSION   WP_000767829
VERSION     WP_000767829.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 84)
  AUTHORS   Winther,K.S. and Gerdes,K.
  TITLE     Ectopic production of VapCs from Enterobacteria inhibits
            translation and trans-activates YoeB mRNA interferase
  JOURNAL   Mol. Microbiol. 72 (4), 918-930 (2009)
   PUBMED   19400780
REFERENCE   2  (residues 1 to 84)
  AUTHORS   Zhang,Y. and Inouye,M.
  TITLE     The inhibitory mechanism of protein synthesis by YoeB, an
            Escherichia coli toxin
  JOURNAL   J. Biol. Chem. 284 (11), 6627-6638 (2009)
   PUBMED   19124462
REFERENCE   3  (residues 1 to 84)
  AUTHORS   Bailey,S.E. and Hayes,F.
  TITLE     Influence of operator site geometry on transcriptional control by
            the YefM-YoeB toxin-antitoxin complex
  JOURNAL   J. Bacteriol. 191 (3), 762-772 (2009)
   PUBMED   19028895
REFERENCE   4  (residues 1 to 84)
  AUTHORS   Christensen-Dalsgaard,M. and Gerdes,K.
  TITLE     Translation affects YoeB and MazF messenger RNA interferase
            activities by different mechanisms
  JOURNAL   Nucleic Acids Res. 36 (20), 6472-6481 (2008)
   PUBMED   18854355
REFERENCE   5  (residues 1 to 84)
  AUTHORS   Kamada,K. and Hanaoka,F.
  TITLE     Conformational change in the catalytic site of the ribonuclease
            YoeB toxin by YefM antitoxin
  JOURNAL   Mol. Cell 19 (4), 497-509 (2005)
   PUBMED   16109374
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            REFSEQ INFORMATION: The reference sequence is identical to P69348.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR010995
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..84
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..84
                     /gene="yoeB"
     Protein         1..84
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin YoeB"
                     /calculated_mol_wt=10084
     Region          1..84
                     /region_name="COG4115"
                     /note="Toxin component of the Txe-Axe toxin-antitoxin
                     module, Txe/YoeB family [Defense mechanisms]"
                     /db_xref="CDD:443291"
ORIGIN      
        1 mkliwseesw ddylywqetd krivkkinel ikdtrrtpfe gkgkpeplkh nlsgfwsrri
       61 teehrlvyav tddslliaac ryhy