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MULTISPECIES: dihydropteroate synthase [Enterobacteriaceae].


LOCUS       WP_000764731             282 aa            linear   BCT 16-DEC-2020
ACCESSION   WP_000764731
VERSION     WP_000764731.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008625.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11613
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..282
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..282
                     /gene="folP"
     Protein         1..282
                     /product="dihydropteroate synthase"
                     /EC_number="2.5.1.15"
                     /GO_function="GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA]"
                     /calculated_mol_wt=30484
     Region          1..282
                     /region_name="folP"
                     /note="dihydropteroate synthase; Provisional; PRK11613"
                     /db_xref="CDD:183230"
     Site            order(22,96,115,117,139,185,217,221,255,257)
                     /site_type="other"
                     /note="substrate binding pocket [chemical binding]"
                     /db_xref="CDD:238380"
     Site            order(198,202..203,241,245,249,264..265)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238380"
     Site            219..221
                     /site_type="active"
                     /note="inhibitor binding site [active]"
                     /db_xref="CDD:238380"
ORIGIN      
        1 mklfaqgtsl dlshphvmgi lnvtpdsfsd ggthnslida vkhanlmina gatiidvgge
       61 strpgaaevs veeelqrvip vveaiaqrfe vwisvdtskp eviresakvg ahiindirsl
      121 sepgaleaaa etglpvclmh mqgnpktmqe apkyddvfae vnryfieqia rceqagiake
      181 kllldpgfgf gknlshnysl larlaefhhf nlpllvgmsr ksmigqllnv gpserlsgsl
      241 acaviaamqg ahiirvhdvk etveamrvve atlsakenkr ye