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LOCUS WP_000761746 347 aa linear BCT 24-DEC-2024 ACCESSION WP_000761746 VERSION WP_000761746.1 KEYWORDS RefSeq. SOURCE Salmonella ORGANISM Salmonella Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae. REFERENCE 1 (residues 1 to 347) AUTHORS Coines,J., Raich,L. and Rovira,C. TITLE Modeling catalytic reaction mechanisms in glycoside hydrolases JOURNAL Curr Opin Chem Biol 53, 183-191 (2019) PUBMED 31731209 REFERENCE 2 (residues 1 to 347) AUTHORS Naumoff,D.G. TITLE Hierarchical classification of glycoside hydrolases JOURNAL Biochemistry (Mosc) 76 (6), 622-635 (2011) PUBMED 21639842 REFERENCE 3 (residues 1 to 347) AUTHORS Vuong,T.V. and Wilson,D.B. TITLE Glycoside hydrolases: catalytic base/nucleophile diversity JOURNAL Biotechnol Bioeng 107 (2), 195-205 (2010) PUBMED 20552664 REFERENCE 4 (residues 1 to 347) AUTHORS Taylor,G. TITLE Sialidases: structures, biological significance and therapeutic potential JOURNAL Curr Opin Struct Biol 6 (6), 830-837 (1996) PUBMED 8994884 REFERENCE 5 (residues 1 to 347) AUTHORS Davies,G. and Henrissat,B. TITLE Structures and mechanisms of glycosyl hydrolases JOURNAL Structure 3 (9), 853-859 (1995) PUBMED 8535779 REFERENCE 6 (residues 1 to 347) AUTHORS Henrissat,B., Callebaut,I., Fabrega,S., Lehn,P., Mornon,J.P. and Davies,G. TITLE Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases JOURNAL Proc Natl Acad Sci U S A 92 (15), 7090-7094 (1995) PUBMED 7624375 REMARK Erratum:[Proc Natl Acad Sci U S A. 1996 May 28;93(11):5674. doi: 10.1073/pnas.93.11.5674. PMID: 8643635] REFERENCE 7 (residues 1 to 347) AUTHORS Roggentin,P., Schauer,R., Hoyer,L.L. and Vimr,E.R. TITLE The sialidase superfamily and its spread by horizontal gene transfer JOURNAL Mol Microbiol 9 (5), 915-921 (1993) PUBMED 7934919 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 10008717 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..347 /organism="Salmonella" /db_xref="taxon:590" Protein 1..347 /product="sialidase family protein" /EC_number="3.2.1.-" /GO_function="GO:0004308 - exo-alpha-sialidase activity [Evidence IEA]" /GO_function="GO:0016997 - alpha-sialidase activity [Evidence IEA]" /GO_process="GO:0005975 - carbohydrate metabolic process [Evidence IEA]" /calculated_mol_wt=38855 Region 4..344 /region_name="COG4692" /note="Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis]" /db_xref="CDD:443727" ORIGIN 1 mklalvnrqv ilpesgtesf qchastlvrl pcgtlvaawf aglregsedt aiwlsryehn 61 iwttpqrvaa regeahwnpv lfypsdklwl fykvgsdvhv wktwfitssd rgftwstpap 121 lvnddilprg pvknklllas ngawiapgsi esperwrafv drssdegkhw sisfvplepd 181 naisgtnval wdgikkgrlw ecclenllrw dgviqptlwe sspghihmll rstrgaifrs 241 dsidygatws varatslpnn nsgidlvsmq dgtlilalnp vngnwgkryp lsliasqdng 301 eswlplldle sdhgeysypa iiseggivhi tytwnrkniv ycrlqtv