SAM hydrolase/SAM-dependent halogenase family protein [Escherichia

LOCUS       WP_000751612             300 aa            linear   BCT 18-FEB-2025
            coli].
ACCESSION   WP_000751612
VERSION     WP_000751612.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 300)
  AUTHORS   Kornfuehrer,T., Romanowski,S., de Crecy-Lagard,V., Hanson,A.D. and
            Eustaquio,A.S.
  TITLE     An Enzyme Containing the Conserved Domain of Unknown Function DUF62
            Acts as a Stereoselective (Rs,Sc)-S-Adenosylmethionine Hydrolase
  JOURNAL   Chembiochem 21 (24), 3495-3499 (2020)
   PUBMED   32776704
REFERENCE   2  (residues 1 to 300)
  AUTHORS   Deng,H. and O'Hagan,D.
  TITLE     The fluorinase, the chlorinase and the duf-62 enzymes
  JOURNAL   Curr Opin Chem Biol 12 (5), 582-592 (2008)
   PUBMED   18675376
REFERENCE   3  (residues 1 to 300)
  AUTHORS   Eustaquio,A.S., Pojer,F., Noel,J.P. and Moore,B.S.
  TITLE     Discovery and characterization of a marine bacterial SAM-dependent
            chlorinase
  JOURNAL   Nat Chem Biol 4 (1), 69-74 (2008)
   PUBMED   18059261
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10004885
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..300
                     /product="SAM hydrolase/SAM-dependent halogenase family
                     protein"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /calculated_mol_wt=32608
     Region          27..297
                     /region_name="COG1912"
                     /note="Stereoselective (R,S)-S-adenosylmethionine
                     hydrolase (adenosine-forming) [Coenzyme transport and
                     metabolism, Defense mechanisms]"
                     /db_xref="CDD:441516"
ORIGIN      
        1 mkktlatlfl ltclgsssay adnalilqtd fslkdgavsa mkgvafgvdh nlkifdlthe
       61 ippyniwega yrlyqtasyw pqgsvfvsvv dpgvgtdrks ivlktkngqy fvspdngtlt
      121 lvaeslgies vreidekanr lkgseksytf hgrdvyaytg arlasgaitf eqvgpelpak
      181 vvelsyqkak atkgevkgni pildiqygnv wsnisdelln qagiklndtl cvtisegsrq
      241 kyagkmpyva sfgdvpegqp mvylnsllnv svalnmdnfa qkhqvasgad wnidvkkcdk