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MULTISPECIES: macrolide transporter subunit MacA [Escherichia].


LOCUS       WP_000746442             371 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_000746442
VERSION     WP_000746442.1
KEYWORDS    RefSeq.
SOURCE      Escherichia
  ORGANISM  Escherichia
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 371)
  AUTHORS   Fitzpatrick,A.W.P., Llabres,S., Neuberger,A., Blaza,J.N., Bai,X.C.,
            Okada,U., Murakami,S., van Veen,H.W., Zachariae,U., Scheres,S.H.W.,
            Luisi,B.F. and Du,D.
  TITLE     Structure of the MacAB-TolC ABC-type tripartite multidrug efflux
            pump
  JOURNAL   Nat Microbiol 2, 17070 (2017)
   PUBMED   28504659
  REMARK    Publication Status: Online-Only
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008606.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11578
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..371
                     /organism="Escherichia"
                     /db_xref="taxon:561"
     gene            1..371
                     /gene="macA"
     Protein         1..371
                     /product="macrolide transporter subunit MacA"
                     /GO_component="GO:0019898 - extrinsic component of
                     membrane [Evidence IEA]"
                     /GO_component="GO:1990195 - macrolide transmembrane
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:1990961 - xenobiotic detoxification by
                     transmembrane export across the plasma membrane [Evidence
                     IEA]"
                     /calculated_mol_wt=40493
     Region          1..370
                     /region_name="PRK11578"
                     /note="macrolide transporter subunit MacA; Provisional"
                     /db_xref="CDD:183211"
ORIGIN      
        1 mkkrktvkkr yvialvivia glitlwriln apvptyqtli vrpgdlqqsv latgkldalr
       61 kvdvgaqvsg qlktlsvaig dkvkkdqllg vidpeqaenq ikeveatlme lraqrqqaea
      121 elklarvtys rqqrlaqtka vsqqdldtaa temavkqaqi gtidaqikrn qasldtaktn
      181 ldytrivapm agevtqittl qgqtviaaqq apniltladm samlvkaqvs eadvihlkpg
      241 qkawftvlgd pltryegqik dvlptpekvn daifyyarfe vpnpngllrl dmtaqvhiql
      301 tdvknvltip lsalgdpvgd nrykvkllrn getrerevti garndtdvei vkgleagdev
      361 vigeakpgaa q