16S rRNA (guanine(966)-N(2))-methyltransferase [Escherichia coli].

LOCUS       WP_000743199             198 aa            linear   BCT 11-DEC-2019
ACCESSION   WP_000743199
VERSION     WP_000743199.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 198)
  AUTHORS   Lesnyak,D.V., Osipiuk,J., Skarina,T., Sergiev,P.V., Bogdanov,A.A.,
            Edwards,A., Savchenko,A., Joachimiak,A. and Dontsova,O.A.
  TITLE     Methyltransferase that modifies guanine 966 of the 16 S rRNA:
            functional identification and tertiary structure
  JOURNAL   J. Biol. Chem. 282 (8), 5880-5887 (2007)
   PUBMED   17189261
REFERENCE   2  (residues 1 to 198)
  AUTHORS   Sergiev,P.V., Bogdanov,A.A. and Dontsova,O.A.
  TITLE     Ribosomal RNA guanine-(N2)-methyltransferases and their targets
  JOURNAL   Nucleic Acids Res. 35 (7), 2295-2301 (2007)
   PUBMED   17389639
REFERENCE   3  (residues 1 to 198)
  AUTHORS   Weitzmann,C., Tumminia,S.J., Boublik,M. and Ofengand,J.
  TITLE     A paradigm for local conformational control of function in the
            ribosome: binding of ribosomal protein S19 to Escherichia coli 16S
            rRNA in the presence of S7 is required for methylation of m2G966
            and blocks methylation of m5C967 by their respective
            methyltransferases
  JOURNAL   Nucleic Acids Res. 19 (25), 7089-7095 (1991)
   PUBMED   1766869
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008157.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10909
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..198
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..198
                     /gene="rsmD"
     Protein         1..198
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase"
                     /EC_number="2.1.1.171"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0031167 - rRNA methylation [Evidence IEA]"
                     /calculated_mol_wt=21577
     Region          1..198
                     /region_name="rsmD"
                     /note="16S rRNA m(2)G966-methyltransferase; Provisional;
                     PRK10909"
                     /db_xref="CDD:236793"
     Site            order(59..65,82..83,108..110,127)
                     /site_type="other"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]"
                     /db_xref="CDD:100107"
ORIGIN      
        1 mkkpnhsgsg qiriiggqwr grklpvpdsp glrpttdrvr etlfnwlapv ivdaqcldcf
       61 agsgalglea lsryaagatl iemdravsqq liknlatlka gnarvvnsna msflaqkgtp
      121 hnivfvdppf rrglleetin lledngwlad etliyvesev englptvpan wslhrekvag
      181 qvayrlyqre aqgesdad