MULTISPECIES: 2-C-methyl-D-erythritol 4-phosphate

LOCUS       WP_000741650             236 aa            linear   BCT 10-JUN-2024
            cytidylyltransferase [Salmonella].
ACCESSION   WP_000741650
VERSION     WP_000741650.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00453.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..236
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..236
                     /gene="ispD"
     Protein         1..236
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /EC_number="2.7.7.60"
                     /GO_function="GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /calculated_mol_wt=25624
     Region          8..232
                     /region_name="ispD"
                     /note="D-ribitol-5-phosphate cytidylyltransferase;
                     PRK00155"
                     /db_xref="CDD:234670"
     Site            order(13,15..20,27,82..85,88,106..108,213)
                     /site_type="active"
                     /note="substrate binding site [active]"
                     /db_xref="CDD:133009"
     Site            order(109,129,137,139,158..163,189..190,192..193,196,
                     201..204,208..209)
                     /site_type="active"
                     /note="dimer interface [active]"
                     /db_xref="CDD:133009"
ORIGIN      
        1 maatlldvca vvpaagfgrr mqtecpkqyl signktileh svhallahpr vtrvviaisp
       61 gdhrfaqlpl anhpqitvvd ggneradsvl aglqavakaq wvlvhdaarp clhqddlarl
      121 laisensrvg gilaspvrdt mkrgepgkna iahtveradl whaltpqffp rellydcltr
      181 alnegatitd easaleycgf hpalvegrad nikvtrpedl alaefyltrt ihqeka