site-specific integrase [Escherichia coli].

LOCUS       WP_000741454             380 aa            linear   BCT 20-MAR-2023
ACCESSION   WP_000741454
VERSION     WP_000741454.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 380)
  AUTHORS   Grainge,I. and Jayaram,M.
  TITLE     The integrase family of recombinase: organization and function of
            the active site
  JOURNAL   Mol Microbiol 33 (3), 449-456 (1999)
   PUBMED   10577069
REFERENCE   2  (residues 1 to 380)
  AUTHORS   Gopaul,D.N. and Duyne,G.D.
  TITLE     Structure and mechanism in site-specific recombination
  JOURNAL   Curr Opin Struct Biol 9 (1), 14-20 (1999)
   PUBMED   10047575
REFERENCE   3  (residues 1 to 380)
  AUTHORS   Esposito,D. and Scocca,J.J.
  TITLE     The integrase family of tyrosine recombinases: evolution of a
            conserved active site domain
  JOURNAL   Nucleic Acids Res 25 (18), 3605-3614 (1997)
   PUBMED   9278480
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10283019
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..380
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..380
                     /product="site-specific integrase"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence
                     IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /calculated_mol_wt=43731
     Region          2..69
                     /region_name="Arm-DNA-bind_1"
                     /note="Bacteriophage lambda integrase, Arm DNA-binding
                     domain; pfam09003"
                     /db_xref="CDD:430365"
     Region          199..373
                     /region_name="INT_Lambda_C"
                     /note="C-terminal catalytic domain of Lambda integrase, a
                     tyrosine-based site-specific recombinase; cd00800"
                     /db_xref="CDD:271181"
     Site            order(199,202..203,205..206,216)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:271181"
     Site            order(228,332,335,355,364)
                     /site_type="active"
                     /db_xref="CDD:271181"
ORIGIN      
        1 maasprshki sipnlyckld krtgkvywqy khplsgrfhs lgtdeneakq vateantiia
       61 eqrtrqilsv nerlermkgr rsditvtewl dkynsiqedr lqhnelrpns yrqkgkpirl
      121 frehcgmqhl kditaldiae iidavkaegh nrmaqvvrmv lidvfkeaqh aghvppgfnp
      181 aqatkqprnr vnrqrlslpe wqaifdsvsr rqpylkcgml lalvtgqrls dicnlkfsdi
      241 wddmlhitqe ktgsklaipl nlkcdalnit lrevisqcrd avvskylvhy rhttsqanrg
      301 dqvsantltt afkkarekcg ikweqgtapt fheqrslser lyreqgldtq kllghksrkm
      361 tdrynddrgk dwiivdikta