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GhoT/OrtT family toxin [Shigella flexneri].


LOCUS       WP_000732115              82 aa            linear   BCT 01-MAR-2025
ACCESSION   WP_000732115
VERSION     WP_000732115.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 82)
  AUTHORS   Islam,S., Benedik,M.J. and Wood,T.K.
  TITLE     Orphan toxin OrtT (YdcX) of Escherichia coli reduces growth during
            the stringent response
  JOURNAL   Toxins (Basel) 7 (2), 299-321 (2015)
   PUBMED   25643179
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 82)
  AUTHORS   Wang,X., Lord,D.M., Hong,S.H., Peti,W., Benedik,M.J., Page,R. and
            Wood,T.K.
  TITLE     Type II toxin/antitoxin MqsR/MqsA controls type V toxin/antitoxin
            GhoT/GhoS
  JOURNAL   Environ Microbiol 15 (6), 1734-1744 (2013)
   PUBMED   23289863
REFERENCE   3  (residues 1 to 82)
  AUTHORS   Wang,X., Lord,D.M., Cheng,H.Y., Osbourne,D.O., Hong,S.H.,
            Sanchez-Torres,V., Quiroga,C., Zheng,K., Herrmann,T., Peti,W.,
            Benedik,M.J., Page,R. and Wood,T.K.
  TITLE     A new type V toxin-antitoxin system where mRNA for toxin GhoT is
            cleaved by antitoxin GhoS
  JOURNAL   Nat Chem Biol 8 (10), 855-861 (2012)
   PUBMED   22941047
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF022213.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF10753.14
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..82
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     Protein         1..82
                     /product="GhoT/OrtT family toxin"
                     /calculated_mol_wt=9531
     Region          29..82
                     /region_name="Toxin_GhoT_OrtT"
                     /note="Toxin GhoT_OrtT; pfam10753"
                     /db_xref="CDD:431472"
ORIGIN      
        1 mkkldarqkm ahicarfihm agrpymflyq hmlvfyavma aiaflitwfl shdkkrirfl
       61 saflvgatwp msfpvallfs lf