MULTISPECIES: dicarboxylate/amino acid:cation symporter

LOCUS       WP_000724200             426 aa            linear   BCT 01-JAN-2025
            [Escherichia].
ACCESSION   WP_000724200
VERSION     WP_000724200.1
KEYWORDS    RefSeq.
SOURCE      Escherichia
  ORGANISM  Escherichia
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 426)
  AUTHORS   Grewer,C., Gameiro,A. and Rauen,T.
  TITLE     SLC1 glutamate transporters
  JOURNAL   Pflugers Arch 466 (1), 3-24 (2014)
   PUBMED   24240778
REFERENCE   2  (residues 1 to 426)
  AUTHORS   Kanai,Y., Clemencon,B., Simonin,A., Leuenberger,M., Lochner,M.,
            Weisstanner,M. and Hediger,M.A.
  TITLE     The SLC1 high-affinity glutamate and neutral amino acid transporter
            family
  JOURNAL   Mol Aspects Med 34 (2-3), 108-120 (2013)
   PUBMED   23506861
REFERENCE   3  (residues 1 to 426)
  AUTHORS   Gesemann,M., Lesslauer,A., Maurer,C.M., Schonthaler,H.B. and
            Neuhauss,S.C.
  TITLE     Phylogenetic analysis of the vertebrate excitatory/neutral amino
            acid transporter (SLC1/EAAT) family reveals lineage specific
            subfamilies
  JOURNAL   BMC Evol Biol 10, 117 (2010)
   PUBMED   20429920
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 426)
  AUTHORS   Kanai,Y. and Hediger,M.A.
  TITLE     The glutamate/neutral amino acid transporter family SLC1:
            molecular, physiological and pharmacological aspects
  JOURNAL   Pflugers Arch 447 (5), 469-479 (2004)
   PUBMED   14530974
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10003465
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Escherichia"
                     /db_xref="taxon:561"
     Protein         1..426
                     /product="dicarboxylate/amino acid:cation symporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /calculated_mol_wt=45129
     Region          2..405
                     /region_name="GltP"
                     /note="Na+/H+-dicarboxylate symporter [Energy production
                     and conversion]; COG1301"
                     /db_xref="CDD:440912"
ORIGIN      
        1 mkkislttmi llalvlgmii gvvlnntasp etaklyaqei sifttiflrl ikmiiaplvv
       61 stlvvgiakm gdakalgrif sktlflfica sllsialgli tvnffmpgtg infvahgaet
      121 tgvvaaepft lkvfishafp tsivdamahn eilqivvfsi flgcsltaig ekgsaivhal
      181 dslahamlkl tgyvmlfapl tvfaaisali aerglavmvs agifmgefyf tmlllwvlli
      241 glaivyvgpc irrltralse pallafttss seaafpgtle kleqfgvspk iasfvlpigy
      301 sfnlvgsmay csfatvfiaq acnihlsige qitmllilml tskgmagvpr asmvviaatl
      361 nqfnipeagl illmgvdpfl dmgrsatnvm snamgaamvs rwegehfgeg crgkalkpne
      421 snvalp