MULTISPECIES: NADH-dependent methylglyoxal reductase

LOCUS       WP_000723710             326 aa            linear   BCT 16-DEC-2020
            [Enterobacteriaceae].
ACCESSION   WP_000723710
VERSION     WP_000723710.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 326)
  AUTHORS   Vogel-Scheel,J., Alpert,C., Engst,W., Loh,G. and Blaut,M.
  TITLE     Requirement of purine and pyrimidine synthesis for colonization of
            the mouse intestine by Escherichia coli
  JOURNAL   Appl. Environ. Microbiol. 76 (15), 5181-5187 (2010)
   PUBMED   20562286
REFERENCE   2  (residues 1 to 326)
  AUTHORS   Di Luccio,E., Elling,R.A. and Wilson,D.K.
  TITLE     Identification of a novel NADH-specific aldo-keto reductase using
            sequence and structural homologies
  JOURNAL   Biochem. J. 400 (1), 105-114 (2006)
   PUBMED   16813561
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            REFSEQ INFORMATION: The reference sequence is identical to
            AAC74841.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR008161
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..326
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..326
                     /gene="ydjG"
     Protein         1..326
                     /product="NADH-dependent methylglyoxal reductase"
                     /EC_number="1.1.1.-"
                     /calculated_mol_wt=36198
     Region          3..319
                     /region_name="AKR_AKR11B2"
                     /note="Escherichia coli NADH-specific methylglyoxal
                     reductase (YdjG) and similar proteins; cd19149"
                     /db_xref="CDD:381375"
     Site            order(19..21,54,59,85,169..170,189,217..223,226,228,239,
                     272,289..291,293,297)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:381375"
     Site            order(54,59,85,136)
                     /site_type="active"
                     /note="catalytic tetrad [active]"
                     /db_xref="CDD:381375"
ORIGIN      
        1 mkkiplgttd itlsrmglgt waigggpawn gdldrqicid tileahrcgi nlidtapgyn
       61 fgnsevivgq alkklpreqv vvetkcgivw erkgslfnkv gdrqlyknls pesireevaa
      121 slqrlgidyi diymthwqsv ppfftpiaet vavlnelkse gkiraigaan vdadhireyl
      181 qygeldiiqa kysildrame nellplcrdn givvqvyspl eqglltgtit rdyvpggara
      241 nkvwfqrenm lkvidmleqw qplcaryqct iptlalawil kqsdlisils gatapeqvre
      301 nvaalninls dadatlmrem aealer