fused tRNA nucleotidyltransferase/2',3'-cyclic phosphodiesterase/2'

LOCUS       WP_000708496             412 aa            linear   BCT 10-JUL-2019
            nucleotidase/phosphatase Cca [Escherichia coli].
ACCESSION   WP_000708496
VERSION     WP_000708496.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 412)
  AUTHORS   Diaz-Mejia,J.J., Babu,M. and Emili,A.
  TITLE     Computational and experimental approaches to chart the Escherichia
            coli cell-envelope-associated proteome and interactome
  JOURNAL   FEMS Microbiol. Rev. 33 (1), 66-97 (2009)
   PUBMED   19054114
REFERENCE   2  (residues 1 to 412)
  AUTHORS   Butland,G., Peregrin-Alvarez,J.M., Li,J., Yang,W., Yang,X.,
            Canadien,V., Starostine,A., Richards,D., Beattie,B., Krogan,N.,
            Davey,M., Parkinson,J., Greenblatt,J. and Emili,A.
  TITLE     Interaction network containing conserved and essential protein
            complexes in Escherichia coli
  JOURNAL   Nature 433 (7025), 531-537 (2005)
   PUBMED   15690043
REFERENCE   3  (residues 1 to 412)
  AUTHORS   Yakunin,A.F., Proudfoot,M., Kuznetsova,E., Savchenko,A., Brown,G.,
            Arrowsmith,C.H. and Edwards,A.M.
  TITLE     The HD domain of the Escherichia coli tRNA nucleotidyltransferase
            has 2',3'-cyclic phosphodiesterase, 2'-nucleotidase, and
            phosphatase activities
  JOURNAL   J. Biol. Chem. 279 (35), 36819-36827 (2004)
   PUBMED   15210699
  REMARK    Erratum:[J Biol Chem. 2004 Dec 24;279(52):54973]
REFERENCE   4  (residues 1 to 412)
  AUTHORS   Seth,M., Thurlow,D.L. and Hou,Y.M.
  TITLE     Poly(C) synthesis by class I and class II CCA-adding enzymes
  JOURNAL   Biochemistry 41 (14), 4521-4532 (2002)
   PUBMED   11926813
REFERENCE   5  (residues 1 to 412)
  AUTHORS   Tomari,Y., Suzuki,T., Watanabe,K. and Ueda,T.
  TITLE     The role of tightly bound ATP in Escherichia coli tRNA
            nucleotidyltransferase
  JOURNAL   Genes Cells 5 (9), 689-698 (2000)
   PUBMED   10971651
REFERENCE   6  (residues 1 to 412)
  AUTHORS   Reuven,N.B. and Deutscher,M.P.
  TITLE     Substitution of the 3' terminal adenosine residue of transfer RNA
            in vivo
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 90 (10), 4350-4353 (1993)
   PUBMED   7685099
REFERENCE   7  (residues 1 to 412)
  AUTHORS   Komine,Y., Adachi,T., Inokuchi,H. and Ozeki,H.
  TITLE     Genomic organization and physical mapping of the transfer RNA genes
            in Escherichia coli K12
  JOURNAL   J. Mol. Biol. 212 (4), 579-598 (1990)
   PUBMED   2184240
REFERENCE   8  (residues 1 to 412)
  AUTHORS   Zhu,L. and Deutscher,M.P.
  TITLE     tRNA nucleotidyltransferase is not essential for Escherichia coli
            viability
  JOURNAL   EMBO J. 6 (8), 2473-2477 (1987)
   PUBMED   3311729
REFERENCE   9  (residues 1 to 412)
  AUTHORS   Cudny,H. and Deutscher,M.P.
  TITLE     High-level overexpression, rapid purification, and properties of
            Escherichia coli tRNA nucleotidyltransferase
  JOURNAL   J. Biol. Chem. 261 (14), 6450-6453 (1986)
   PUBMED   3516995
REFERENCE   10 (residues 1 to 412)
  AUTHORS   McGann,R.G. and Deutscher,M.P.
  TITLE     Purification and characterization of a mutant tRNA
            nucleotidyltransferase
  JOURNAL   Eur. J. Biochem. 106 (1), 321-328 (1980)
   PUBMED   6176445
REFERENCE   11 (residues 1 to 412)
  AUTHORS   Deutscher,M.P.
  TITLE     Preparation of cells permeable to macromolecules by treatment with
            toluene: studies of transfer ribonucleic acid
            nucleotidyltransferase
  JOURNAL   J. Bacteriol. 118 (2), 633-639 (1974)
   PUBMED   4597454
REFERENCE   12 (residues 1 to 412)
  AUTHORS   Foulds,J., Hilderman,R.H. and Deutscher,M.P.
  TITLE     Mapping of the locus for Escherichia coli transfer ribonucleic acid
            nucleotidyltransferase
  JOURNAL   J. Bacteriol. 118 (2), 628-632 (1974)
   PUBMED   4597453
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR007479
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..412
                     /gene="cca"
     Protein         1..412
                     /product="fused tRNA nucleotidyltransferase/2',3'-cyclic
                     phosphodiesterase/2' nucleotidase/phosphatase Cca"
                     /EC_number="2.7.7.72"
                     /calculated_mol_wt=46451
     Region          1..409
                     /region_name="cca"
                     /note="multifunctional CCA addition/repair protein;
                     PRK10885"
                     /db_xref="CDD:182810"
ORIGIN      
        1 mkiylvggav rdallglpvk drdwvvvgst pqemldagyq qvgrdfpvfl hpqtheeyal
       61 arterksgsg ytgftcyaap dvtleddlkr rdltinalaq ddngeiidpy nglgdlqnrl
      121 lrhvspafge dplrvlrvar faaryahlgf riadetltlm remthagele hltpervwke
      181 tenalttrnp qvffqvlrdc galrvlfpei dalfgvpapa rwhpeidtgi htlmtlsmaa
      241 mlspqvdvrf ttlchdlgkg ltppelwprh hghgpagvkl veqlcqrlrv pneirdlarl
      301 vaefhdliht fpmlnpktiv klfdsidawr kpqrveqlal tseadvrgrt gfesadypqg
      361 rwlreaweva qsvptkavve agfkgveire eltrrriaav aswkeqrcpk pe