MULTISPECIES: MFS transporter [Shigella].

LOCUS       WP_000701054             389 aa            linear   BCT 28-JUL-2024
ACCESSION   WP_000701054
VERSION     WP_000701054.1
KEYWORDS    RefSeq.
SOURCE      Shigella
  ORGANISM  Shigella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 389)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 389)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13023516
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..389
                     /organism="Shigella"
                     /db_xref="taxon:620"
     Protein         1..389
                     /product="MFS transporter"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=39914
     Region          7..374
                     /region_name="MFS_NepI_like"
                     /note="Purine ribonucleoside efflux pump NepI and similar
                     transporters of the Major Facilitator Superfamily;
                     cd17324"
                     /db_xref="CDD:340882"
     Site            order(17..18,21..22,25,57,107..108,110..112,115,135,
                     138..139,142,210,213..214,217..219,222,250,254,303..304,
                     308,312,327,330..331,334..335,338)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340882"
ORIGIN      
        1 mkinypllal aigafgigtt efspmgllpv iargvdvsip aagmlisaya vgvmvgaplm
       61 tlllshrarr saliflmaif tlgnvlsaia pdymtlmlsr iltslnhgaf fglgsvvaas
      121 vvpkhkqasa vatmfmgltl aniggvpaat wlgetigwrm sflataglgv ismvslffsl
      181 pkggtgarpe vkkelavlmr pqvlsalltt vlgagamftl ytyispvlqs ithatpvfvt
      241 amlvligvgf signylggkl adrsvngtlk gfllllmvim laipflarne fgaaismvvw
      301 gaatfavvpp lqmrvmhvas eapglsssvn igafnlgnal gaaaggavis aglgysfvpv
      361 tgaivaglal llvfmsarkq petvcvans