MULTISPECIES: dTDP-glucose 4,6-dehydratase [Shigella].

LOCUS       WP_000699404             361 aa            linear   BCT 17-JUN-2024
ACCESSION   WP_000699404
VERSION     WP_000699404.1
KEYWORDS    RefSeq.
SOURCE      Shigella
  ORGANISM  Shigella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01181.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Shigella"
                     /db_xref="taxon:620"
     gene            1..361
                     /gene="rfbB"
     Protein         1..361
                     /product="dTDP-glucose 4,6-dehydratase"
                     /EC_number="4.2.1.46"
                     /GO_function="GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA]"
                     /GO_process="GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=40444
     Region          1..352
                     /region_name="PRK10084"
                     /note="dTDP-glucose 4,6 dehydratase; Provisional"
                     /db_xref="CDD:236649"
     Site            order(7,9..12,32..35,37..38,57..59,80..82,84,99,131..133,
                     167,171,194..197)
                     /site_type="other"
                     /note="NAD binding site [chemical binding]"
                     /db_xref="CDD:187557"
     Site            order(84..86,133..135,167,194..196,205..207,210..211,
                     222..224,229,231,266,297,300,304)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:187557"
     Site            order(88,90,93..94,97,101..102,105,109,112,139,158,
                     160..161,163..166,169,172..173,176..177,180..181,183..185,
                     301)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:187557"
     Site            order(100,133,167,171)
                     /site_type="active"
                     /db_xref="CDD:187557"
ORIGIN      
        1 mkilvtggag figsavvrhi inntqdsvvn vdkltyagnl esladvsdse ryafehadic
       61 davamsrifa qhqpdavmhl aaeshvdrsi tgpaafietn ivgtyvllea arnywsalnd
      121 ekkksfrfhh istdevygdl phpdeannne alplftetta yapsspysas kassdhlvra
      181 wkrtyglpti vtncsnnygp yhfpeklipl vilnalegka lpiygkgdqi rdwlyvedha
      241 ralytvvteg kagetynigg hnekknidvv lticdlldei vpkeksyreq ityvadrpgh
      301 drryaidadk isrelgwkpq etfesgirkt vewylantnw venvksgtyq swieqnyegr
      361 q