MULTISPECIES: dTDP-glucose 4,6-dehydratase [Salmonella].

LOCUS       WP_000697840             361 aa            linear   BCT 17-JUN-2024
ACCESSION   WP_000697840
VERSION     WP_000697840.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01181.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..361
                     /gene="rfbB"
     Protein         1..361
                     /product="dTDP-glucose 4,6-dehydratase"
                     /EC_number="4.2.1.46"
                     /GO_function="GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA]"
                     /GO_process="GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=40588
     Region          1..352
                     /region_name="PRK10084"
                     /note="dTDP-glucose 4,6 dehydratase; Provisional"
                     /db_xref="CDD:236649"
     Site            order(7,9..12,32..35,37..38,57..59,80..82,84,99,131..133,
                     167,171,194..197)
                     /site_type="other"
                     /note="NAD binding site [chemical binding]"
                     /db_xref="CDD:187557"
     Site            order(84..86,133..135,167,194..196,205..207,210..211,
                     222..224,229,231,266,297,300,304)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:187557"
     Site            order(88,90,93..94,97,101..102,105,109,112,139,158,
                     160..161,163..166,169,172..173,176..177,180..181,183..185,
                     301)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:187557"
     Site            order(100,133,167,171)
                     /site_type="active"
                     /db_xref="CDD:187557"
ORIGIN      
        1 mkilitggag figsavvrhi ikntqdtvvn idkltyagnl eslsdisesn rynfehadic
       61 dsaeitrife qyqpdavmhl aaeshvdrsi tgpaafietn ivgtyallev arkywsalge
      121 dkknnfrfhh istdevygdl phpdevensv tlplftetta yapsspysas kassdhlvra
      181 wrrtyglpti vtncsnnygp yhfpeklipl vilnalegkp lpiygkgdqi rdwlyvedha
      241 ralhmvvteg kagetynigg hnekknldvv fticdlldei vpkatsyreq ityvadrpgh
      301 drryaidagk isrelgwkpl etfesgirkt vewylantqw vnnvksgayq swieqnyegr
      361 q