MULTISPECIES: 5'-methylthioadenosine/S-adenosylhomocysteine

LOCUS       WP_000689821             232 aa            linear   BCT 03-JUN-2024
            nucleosidase [Salmonella].
ACCESSION   WP_000689821
VERSION     WP_000689821.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 232)
  AUTHORS   Sekowska,A. and Danchin,A.
  TITLE     The methionine salvage pathway in Bacillus subtilis
  JOURNAL   BMC Microbiol 2, 8 (2002)
   PUBMED   12022921
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 232)
  AUTHORS   Lee,J.E., Cornell,K.A., Riscoe,M.K. and Howell,P.L.
  TITLE     Structure of E. coli 5'-methylthioadenosine/S-adenosylhomocysteine
            nucleosidase reveals similarity to the purine nucleoside
            phosphorylases
  JOURNAL   Structure 9 (10), 941-953 (2001)
   PUBMED   11591349
REFERENCE   3  (residues 1 to 232)
  AUTHORS   Sekowska,A. and Danchin,A.
  TITLE     Identification of yrrU as the methylthioadenosine nucleosidase gene
            in Bacillus subtilis
  JOURNAL   DNA Res 6 (5), 255-264 (1999)
   PUBMED   10574451
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01704.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..232
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..232
                     /gene="mtnN"
     Protein         1..232
                     /product="5'-methylthioadenosine/S-adenosylhomocysteine
                     nucleosidase"
                     /EC_number="3.2.2.16"
                     /EC_number="3.2.2.9"
                     /GO_function="GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA]"
                     /GO_function="GO:0008930 - methylthioadenosine
                     nucleosidase activity [Evidence IEA]"
                     /GO_process="GO:0009164 - nucleoside catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /calculated_mol_wt=24315
     Region          1..230
                     /region_name="PRK05584"
                     /note="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /db_xref="CDD:180148"
     Site            order(8..9,12,50..51,76..78,150..151,171..174,193,
                     196..197,199,212)
                     /site_type="active"
                     /db_xref="CDD:350159"
     Site            order(10,31,47,49..54,56..57,60..61,63..65,97,99,149..151,
                     173,177,180..181,183..186)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:350159"
ORIGIN      
        1 mkigiigame eevtllrdki dnrqtitlgg ceiytgqlng tevallksgi gkvaaalgat
       61 lllehckpdv iintgsaggl astlkvgdiv vsdearyhda dvtafgyeyg qlpgcpagfk
      121 addkliaaae scirelnlna vrglivsgda fingsvglak irhnfpdava vemeataiah
      181 vchnfnvpfv vvraisdvad qqshlsfdef lavaakqstl mvetlvqkla hg