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5-oxoprolinase subunit PxpA [Escherichia coli].


LOCUS       WP_000687164             244 aa            linear   BCT 02-JUN-2019
ACCESSION   WP_000687164
VERSION     WP_000687164.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 244)
  AUTHORS   Niehaus,T.D., Elbadawi-Sidhu,M., de Crecy-Lagard,V., Fiehn,O. and
            Hanson,A.D.
  TITLE     Discovery of a widespread prokaryotic 5-oxoprolinase that was
            hiding in plain sight
  JOURNAL   J. Biol. Chem. 292 (39), 16360-16367 (2017)
   PUBMED   28830929
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF003812.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK05406
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..244
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..244
                     /gene="pxpA"
     Protein         1..244
                     /product="5-oxoprolinase subunit PxpA"
                     /EC_number="3.5.2.9"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=25733
     Region          3..242
                     /region_name="LamB_YcsF_YbgL_like"
                     /note="Escherichia coli putative lactam utilization
                     protein YbgL and similar proteins; cd10800"
                     /db_xref="CDD:212111"
     Site            order(8,57,68,104,106..107,111,160,163,171,174,218)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:212111"
ORIGIN      
        1 mkidlnadlg egctsdaell tlvssaniac gfhagdaqtm qacvreaikn gvaigahpsf
       61 pdrknfgrsa mqlppetvya qtlyqigala titraqggvm rhvkphgmly nqaakeaqla
      121 daiaravyac dpalvlvgla gseliragkq yglttreevf adrgyqadgs lvprsqsgal
      181 iedeeqalaq tlemvqhgrv ksitgewatv taqtvclhgd gehalafarr lrsafaekgi
      241 vvaa