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MULTISPECIES: LysR family transcriptional regulator


LOCUS       WP_000679972             317 aa            linear   BCT 01-JAN-2025
            [Enterobacteriaceae].
ACCESSION   WP_000679972
VERSION     WP_000679972.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 317)
  AUTHORS   Maddocks,S.E. and Oyston,P.C.F.
  TITLE     Structure and function of the LysR-type transcriptional regulator
            (LTTR) family proteins
  JOURNAL   Microbiology (Reading) 154 (Pt 12), 3609-3623 (2008)
   PUBMED   19047729
REFERENCE   2  (residues 1 to 317)
  AUTHORS   Schell,M.A.
  TITLE     Molecular biology of the LysR family of transcriptional regulators
  JOURNAL   Annu Rev Microbiol 47, 597-626 (1993)
   PUBMED   8257110
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10444078
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     Protein         1..317
                     /product="LysR family transcriptional regulator"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /calculated_mol_wt=35941
     Region          5..64
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          95..290
                     /region_name="PBP2_LTTR_like_4"
                     /note="TThe C-terminal substrate binding domain of an
                     uncharacterized LysR-type transcriptional regulator,
                     contains the type 2 periplasmic binding fold; cd08440"
                     /db_xref="CDD:176131"
     Site            order(109..110,112..113,116,120,122..128,220..225,
                     231..232,234..235)
                     /site_type="other"
                     /note="putative dimerization interface [polypeptide
                     binding]"
                     /db_xref="CDD:176131"
ORIGIN      
        1 mkhelssmka fvilaesssf nnaakllnit qpaltrrikk meedlhiqlf erttrkvtlt
       61 kagkrllpea relikkfdet lfnirdmnay hrgmvtlaci ptavfyflpl aigkfnelyp
      121 nikvrileqg tnncmesvlc nesdfginmn nvtnssidft plvnepfvla crrdhplakk
      181 qlvewqelvg ykmigvrsss gnrllieqql adkpwkldwf yevrhlstsl glveaglgis
      241 alpglampha pyssiigipl vepvirrtlg iirrkdavls paaerffall inlwtddkdn
      301 lwtniverqr halqeig