MULTISPECIES: DNA polymerase III subunit beta [Enterobacteriaceae].

LOCUS       WP_000673464             366 aa            linear   BCT 23-MAY-2024
ACCESSION   WP_000673464
VERSION     WP_000673464.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 366)
  AUTHORS   McGrath,A.E., Martyn,A.P., Whittell,L.R., Dawes,F.E., Beck,J.L.,
            Dixon,N.E., Kelso,M.J. and Oakley,A.J.
  TITLE     Crystal structures and biochemical characterization of DNA sliding
            clamps from three Gram-negative bacterial pathogens
  JOURNAL   J Struct Biol 204 (3), 396-405 (2018)
   PUBMED   30366028
  REMARK    Erratum:[J Struct Biol. 2019 Aug 1;207(2):234. PMID: 31097372]
REFERENCE   2  (residues 1 to 366)
  AUTHORS   Gui,W.J., Lin,S.Q., Chen,Y.Y., Zhang,X.E., Bi,L.J. and Jiang,T.
  TITLE     Crystal structure of DNA polymerase III beta sliding clamp from
            Mycobacterium tuberculosis
  JOURNAL   Biochem Biophys Res Commun 405 (2), 272-277 (2011)
   PUBMED   21219854
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00663.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..366
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..366
                     /gene="dnaN"
     Protein         1..366
                     /product="DNA polymerase III subunit beta"
                     /EC_number="2.7.7.7"
                     /GO_component="GO:0009360 - DNA polymerase III complex
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /calculated_mol_wt=40456
     Region          1..366
                     /region_name="PRK05643"
                     /note="DNA polymerase III subunit beta; Validated"
                     /db_xref="CDD:235541"
     Site            order(24,73,80,198)
                     /site_type="other"
                     /note="putative DNA binding surface [nucleotide binding]"
                     /db_xref="CDD:238082"
     Site            order(74,77,103,105,272,303..304)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238082"
     Site            order(172,174..177,320,362..365)
                     /site_type="active"
                     /note="beta-clamp/clamp loader binding surface [active]"
                     /db_xref="CDD:238082"
     Site            order(172,174..175,247,282,295..296,323,362..365)
                     /site_type="active"
                     /note="beta-clamp/translesion DNA polymerase binding
                     surface [active]"
                     /db_xref="CDD:238082"
ORIGIN      
        1 mkftverehl lkplqqvsgp lggrptlpil gnlllqvadg tlsltgtdle memvarvalv
       61 qphepgattv parkffdicr glpegaeiav qlegermlvr sgrsrfslst lpaadfpnld
      121 dwqseveftl pqatmkrlie atqfsmahqd vryylngmlf etegeelrtv atdghrlavc
      181 smpigqslps hsvivprkgv ielmrmldgg dnplrvqigs nnirahvgdf iftsklvdgr
      241 fpdyrrvlpk npdkhleagc dllkqafara ailsnekfrg vrlyvsenql kitannpeqe
      301 eaeeildvty sgaemeigfn vsyvldvlna lkcenvrmml tdsvssvqie daasqsaayv
      361 vmpmrl