Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: MFS transporter [Salmonella].


LOCUS       WP_000660244             396 aa            linear   BCT 31-MAR-2023
ACCESSION   WP_000660244
VERSION     WP_000660244.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 396)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 396)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13024787
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..396
                     /product="MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=42650
     Region          13..377
                     /region_name="MFS_YfcJ_like"
                     /note="Escherichia coli YfcJ, YhhS, and similar
                     transporters of the Major Facilitator Superfamily;
                     cd17489"
                     /db_xref="CDD:341042"
     Site            order(20..21,24..25,28,61,111..112,114..116,119,139,
                     142..143,146,216,219..220,223..225,228,254,258,307..308,
                     312,316,332,335..336,339..340,343)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:341042"
ORIGIN      
        1 mkeklwtkdf waitivsfii ffvfyvlltl lpiyiadrlh asadkagllv tcflaaaivi
       61 rpfagqwvgk ysnkkilvls slaflvital ypvchsiesl lfirvlhgit fgvittvkgt
      121 isarlipasr rgegisffsl amglamvvgp wiglnmarwd aftaafwlcs avaalgivls
      181 livtvppvir hadgskpnlg fsamfdraal pfalvtffmt fsyagvsafl alyareldlm
      241 aaasnfllcy aillmicrtf tgnicdkkgp kyvvypclla ftiglvalgy tngsimmiis
      301 ggligigygs vtpvfqtqii ssvephkigv anslffnamd agmaigafim gmmvesvgyr
      361 miyvagavlv vlagalyavq mkkrgvmplv stselh