MULTISPECIES: MFS transporter [Enterobacteriaceae].

LOCUS       WP_000660231             396 aa            linear   BCT 31-MAR-2023
ACCESSION   WP_000660231
VERSION     WP_000660231.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 396)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 396)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13024787
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     Protein         1..396
                     /product="MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=42775
     Region          25..379
                     /region_name="MFS_YfcJ_like"
                     /note="Escherichia coli YfcJ, YhhS, and similar
                     transporters of the Major Facilitator Superfamily;
                     cd17489"
                     /db_xref="CDD:341042"
     Site            order(25,28,61,111..112,114..116,119,139,142..143,146,216,
                     219..220,223..225,228,254,258,307..308,312,316,332,
                     335..336,339..340,343)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:341042"
ORIGIN      
        1 mkeklwtkdf waitiisfii ffvfyvlltl lpiyisdrlh aspdkagllv tlfliaaivi
       61 rpfagqwvgk ysnktilvls slaflvvtal ypfchsiesl lfirvlhgit fgvittvkgt
      121 isarlipasr rgegisffsl amglamvvgp wiglnmarwe afnmafwlct gvaavgiils
      181 limtvppvis hadgskpkmg faamfdraal pfamvtffmt fsyagvsafl alyarelnlm
      241 saasnfllcy aiflmicrtf tgnvcdkkgp kyvvypcllf ftvglvvlgy tqgsvmmvvs
      301 galigigygs vtpvfqtqii ssvephkigv anslffnamd aglalgacvm gmmvahtgyr
      361 miyllgallv vvaggvyalq mkgksgvalv vakeih