winged helix-turn-helix domain-containing protein [Escherichia

LOCUS       WP_000639305             270 aa            linear   BCT 20-JAN-2025
            coli].
ACCESSION   WP_000639305
VERSION     WP_000639305.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 270)
  AUTHORS   Aravind,L., Anantharaman,V., Balaji,S., Babu,M.M. and Iyer,L.M.
  TITLE     The many faces of the helix-turn-helix domain: transcription
            regulation and beyond
  JOURNAL   FEMS Microbiol Rev 29 (2), 231-262 (2005)
   PUBMED   15808743
REFERENCE   2  (residues 1 to 270)
  AUTHORS   Rosinski,J.A. and Atchley,W.R.
  TITLE     Molecular evolution of helix-turn-helix proteins
  JOURNAL   J Mol Evol 49 (3), 301-309 (1999)
   PUBMED   10473770
REFERENCE   3  (residues 1 to 270)
  AUTHORS   Wintjens,R. and Rooman,M.
  TITLE     Structural classification of HTH DNA-binding domains and
            protein-DNA interaction modes
  JOURNAL   J Mol Biol 262 (2), 294-313 (1996)
   PUBMED   8831795
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10007860
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..270
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..270
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /calculated_mol_wt=30827
     Region          1..114
                     /region_name="CadC1"
                     /note="DNA-binding winged helix-turn-helix (wHTH) domain
                     [Transcription]; COG3710"
                     /db_xref="CDD:442924"
ORIGIN      
        1 miyiindevr fnsssnklts lltseevilt ypagkclkll ldnaysvvsh nqffekvwsd
       61 ssadvatntl yqnismirrs freissatif ndvirtvprk gfkineeisi tvldnnhnen
      121 esveseengt hteninknhi akgifttknt llivcffaaw givyissyff dmafqsksht
      181 ikkidafsny aqhptqegcs yfydnkyfns vdmlspiiek lqkmeincki hpyiyiatnd
      241 smsgfyaftc sqmlnsespn ncnslyykae