bestrophin family protein [Shigella flexneri].

LOCUS       WP_000635579             321 aa            linear   BCT 02-JAN-2025
ACCESSION   WP_000635579
VERSION     WP_000635579.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 321)
  AUTHORS   Qu,Z. and Hartzell,H.C.
  TITLE     Bestrophin Cl- channels are highly permeable to HCO3-
  JOURNAL   Am J Physiol Cell Physiol 294 (6), C1371-C1377 (2008)
   PUBMED   18400985
REFERENCE   2  (residues 1 to 321)
  AUTHORS   Tsunenari,T., Sun,H., Williams,J., Cahill,H., Smallwood,P.,
            Yau,K.W. and Nathans,J.
  TITLE     Structure-function analysis of the bestrophin family of anion
            channels
  JOURNAL   J Biol Chem 278 (42), 41114-41125 (2003)
   PUBMED   12907679
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10007980
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     Protein         1..321
                     /product="bestrophin family protein"
                     /GO_function="GO:0005254 - chloride channel activity
                     [Evidence IEA]"
                     /calculated_mol_wt=36609
     Region          18..320
                     /region_name="YneE"
                     /note="Predicted membrane chloride channel, bestrophin
                     family [Inorganic ion transport and metabolism]; COG3781"
                     /db_xref="CDD:442995"
ORIGIN      
        1 mivitfnrat fprlkitmiv rpqqhwlrri fvwhgsvlsk issrlllnfl fsiavifmlp
       61 wythlgikft lapfsilgva iaiflgfrnn agyaryvear klwgqlmias rsllrevktt
      121 lpdsasvref arlqiafahc lrmtlrkqpq aevlahylkt gdlqrvlasn spanrillim
      181 gewlavqrrn gqlsdilfis lndrlndisa vlagceriay tpipfaytli lhrtvylfci
      241 mlpfalvvdl hymtpfisvl isytfisldc laeeledpfg tenndlplda icnaieidll
      301 qmndeaeipa kilpdrhyql t