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MULTISPECIES: nucleotide 5'-monophosphate nucleosidase PpnN


LOCUS       WP_000627995             454 aa            linear   BCT 05-JAN-2022
            [Enterobacteriaceae].
ACCESSION   WP_000627995
VERSION     WP_000627995.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 454)
  AUTHORS   Chau,N.Y.E., Perez-Morales,D., Elhenawy,W., Bustamante,V.H.,
            Zhang,Y.E. and Coombes,B.K.
  TITLE     (p)ppGpp-Dependent Regulation of the Nucleotide Hydrolase PpnN
            Confers Complement Resistance in Salmonella enterica Serovar
            Typhimurium
  JOURNAL   Infect Immun 89 (2), e00639-20 (2021)
   PUBMED   33139383
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 454)
  AUTHORS   Baerentsen,R.L., Brodersen,D.E. and Zhang,Y.E.
  TITLE     Evolution of the bacterial nucleosidase PpnN and its relation to
            the stringent response
  JOURNAL   Microb Cell 6 (9), 450-453 (2019)
   PUBMED   31528633
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 454)
  AUTHORS   Zhang,Y.E., Baerentsen,R.L., Fuhrer,T., Sauer,U., Gerdes,K. and
            Brodersen,D.E.
  TITLE     (p)ppGpp Regulates a Bacterial Nucleosidase by an Allosteric
            Two-Domain Switch
  JOURNAL   Mol Cell 74 (6), 1239-1249 (2019)
   PUBMED   31023582
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF038390.1
            Evidence Source    :: NCBIFAM
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..454
                     /gene="ppnN"
     Protein         1..454
                     /product="nucleotide 5'-monophosphate nucleosidase PpnN"
                     /EC_number="3.2.2.10"
                     /EC_number="3.2.2.4"
                     /calculated_mol_wt=50841
     Region          2..452
                     /region_name="Nsidase_PpnN"
                     /note="nucleotide 5'-monophosphate nucleosidase PpnN;
                     NF038390"
                     /db_xref="CDD:468501"
ORIGIN      
        1 mithisplgs mdmlsqlevd mlkrtassdl yqlfrncsla vlnsgsltdn skellsrfen
       61 fdinvlrrer gvklelinpp eeafvdgrii ralqanlfav lrdilfvygq ihntvrfpnl
      121 nldnsvhitn lvfsilrnar alhvgeapnm vvcwgghsin eneylyarrv gnqlglreln
      181 ictgcgpgam eapmkgaavg haqqrykdsr figmtepsii aaeppnplvn eliimpdiek
      241 rleafvriah giiifpggvg taeellyllg ilmnpankdq vlpliltgpk esadyfrvld
      301 efvvhtlgen arrhyriiid daaevarqmk ksmplvkenr rdtgdaysfn wsmriapdlq
      361 mpfepshenm anlklypdqp vevlaadlrr afsgivagnv kevgiraiee fgpykingdk
      421 eimrrmddll qgfvaqhrmk lpgsayipcy eict