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phosphatase PAP2/dual specificity phosphatase family protein


LOCUS       WP_000627338             438 aa            linear   BCT 13-APR-2019
            [Escherichia coli].
ACCESSION   WP_000627338
VERSION     WP_000627338.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 12932287
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..438
                     /product="phosphatase PAP2/dual specificity phosphatase
                     family protein"
                     /calculated_mol_wt=50564
     Region          55..205
                     /region_name="PAP2_Aur1_like"
                     /note="PAP2_like proteins, Aur1_like subfamily. Yeast
                     Aur1p or Ipc1p is necessary for the addition of inositol
                     phosphate to ceramide, an essential step in yeast
                     sphingolipid synthesis, and is the target of several
                     antifungal compounds such as aureobasidin; cd03386"
                     /db_xref="CDD:239481"
     Site            order(106,114,140..142,176,182,186)
                     /site_type="active"
                     /db_xref="CDD:239481"
     Region          303..437
                     /region_name="DSP_bac"
                     /note="unknown subfamily of bacterial and plant dual
                     specificity protein phosphatases; cd14527"
                     /db_xref="CDD:350376"
ORIGIN      
        1 miterrnvll qgagwlllla pfffftygsl nqftavqdfn shdipsqvfg wetaipflpw
       61 tivpywsldl lygfslfvcs stfeqrrlvh rlilatvmac cgfflyplkf sfirpevsgv
      121 tgwlfsqlel fdlpynqsps lhivlcwllw rhfrqhlavr wrkvcggwfl liaismlttw
      181 qhhfidvitg lavgmlidwm ipvdrrwnyq kpdqrrikia lpyvvgacac ivlmelmmmv
      241 qlwwsvwlcw pvlslliigr gygglgaitt gkdsqgklpp avywltlpwr igmwlsmrwf
      301 crrlepvskm tagvylgafp rhipaqnavl dvtfefprgr atkdrlyfcv pmldlvvpee
      361 gelrqavaml etlreeqgsv lvhcalglsr salvvaawll cyghcktvde aisfirarrs
      421 hivlkeehka mlklwenr