MULTISPECIES: aspartate 1-decarboxylase [Enterobacteriaceae].

LOCUS       WP_000621515             126 aa            linear   BCT 09-JUN-2024
ACCESSION   WP_000621515
VERSION     WP_000621515.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 126)
  AUTHORS   Sun,Q., Li,X., Perez,L.M., Shi,W., Zhang,Y. and Sacchettini,J.C.
  TITLE     The molecular basis of pyrazinamide activity on Mycobacterium
            tuberculosis PanD
  JOURNAL   Nat Commun 11 (1), 339 (2020)
   PUBMED   31953389
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 126)
  AUTHORS   Shi,W., Chen,J., Feng,J., Cui,P., Zhang,S., Weng,X., Zhang,W. and
            Zhang,Y.
  TITLE     Aspartate decarboxylase (PanD) as a new target of pyrazinamide in
            Mycobacterium tuberculosis
  JOURNAL   Emerg Microbes Infect 3 (8), e58 (2014)
   PUBMED   26038753
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00223.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..126
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..126
                     /gene="panD"
     Protein         1..126
                     /product="aspartate 1-decarboxylase"
                     /EC_number="4.1.1.11"
                     /GO_function="GO:0004068 - aspartate 1-decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006523 - alanine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=13703
     Region          1..126
                     /region_name="panD"
                     /note="L-aspartate-alpha-decarboxylase; TIGR00223"
                     /db_xref="CDD:129327"
     Site            order(3..7,9,11..12,20..23,37,39,42..43,47,49,52,54..58,
                     74..75,77..78,86,90..92,101)
                     /site_type="other"
                     /note="tetramerization interface [polypeptide binding]"
                     /db_xref="CDD:132994"
     Site            order(9,11,24..25,58)
                     /site_type="active"
                     /db_xref="CDD:132994"
ORIGIN      
        1 mirtmlqgkl hrvkvthadl hyegscaidq dfldaagile neaidiwnvt ngkrfstyai
       61 aaergsriis vngaaahcas vgdiviiasf vtmpdeeart wrpnvayfeg dnemkrtaka
      121 ipvqva