ATP-dependent endonuclease [Escherichia coli].

LOCUS       WP_000599788             552 aa            linear   BCT 02-JAN-2025
ACCESSION   WP_000599788
VERSION     WP_000599788.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 12109662
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..552
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..552
                     /product="ATP-dependent endonuclease"
                     /calculated_mol_wt=63407
     Region          1..375
                     /region_name="DUF2813"
                     /note="Protein of unknown function (DUF2813); pfam11398"
                     /db_xref="CDD:431868"
     Region          376..472
                     /region_name="TOPRIM_OLD"
                     /note="topoisomerase-primase (TOPRIM) nucleotidyl
                     transferase/hydrolase domain of the type found in
                     bacterial and archaeal nucleases of the OLD (overcome
                     lysogenization defect) family. The bacteriophage P2 OLD
                     protein, which has DNase as well as RNase activity;
                     cd01026"
                     /db_xref="CDD:173776"
     Site            order(385..386,389,438,440)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:173776"
     Site            order(385,438)
                     /site_type="other"
                     /note="putative metal-binding site [ion binding]"
                     /db_xref="CDD:173776"
ORIGIN      
        1 milerveivg frginrlslm leqnnvlige nawgksslld altlllspes dlyhferddf
       61 wfppgdingr ehhlhiiltf reslpgrhrv rryrpleacw tpctdgyhri fyrlegesae
      121 dgsvmtlrsf ldkdghpidv edindqahhl vrlmpvlrlr darfmrrirn gtvpnvpnve
      181 vtarqldfla relsshpqnl sdgqirqgls amvqllehyf seqgagqary rlmrrrasne
      241 qrswryldii nrmidrpggr syrvillglf atllqakgtl rldkdarpll liedpetrlh
      301 pimlsvawhl lnllplqria ttnsgellsl tpvehvcrlv ressrvaawr lgpsglsted
      361 srrisfhirf nrpsslfarc wllvegetet wvinelarqc ghhfdaegik viefaqsglk
      421 plvkfarrmg iewhvlvdgd eagkkyaatv rsllnndrea erehltalpa ldmehfmyrq
      481 gfsdvfhrva qipenvpmnl rkiiskaihr sskpdlaiev ameagrrgvd svptllkkmf
      541 srvlwlargr ad