MULTISPECIES: ADP-glyceromanno-heptose 6-epimerase

LOCUS       WP_000587764             310 aa            linear   BCT 16-DEC-2020
            [Enterobacteriaceae].
ACCESSION   WP_000587764
VERSION     WP_000587764.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008360.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11150
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..310
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..310
                     /gene="rfaD"
     Protein         1..310
                     /product="ADP-glyceromanno-heptose 6-epimerase"
                     /EC_number="5.1.3.20"
                     /GO_function="GO:0008712 - ADP-glyceromanno-heptose
                     6-epimerase activity [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=34762
     Region          1..308
                     /region_name="rfaD"
                     /note="ADP-L-glycero-D-mannoheptose-6-epimerase;
                     Provisional; PRK11150"
                     /db_xref="CDD:182998"
     Site            order(5..6,9..11,30..32,38,53,75..77,79,88,92,96,114..116,
                     140,144,167..168,170,177..178)
                     /site_type="other"
                     /note="NADP binding site [chemical binding]"
                     /db_xref="CDD:187559"
     Site            order(33..34,36..37,39,42..43,45..50,52,84..87,90,94,98,
                     131,135..139,142,146,149..150,153)
                     /site_type="other"
                     /note="homopentamer interface [polypeptide binding]"
                     /db_xref="CDD:187559"
     Site            order(81,169,180..182,184,187,209,243)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:187559"
     Site            order(93,116,140,144)
                     /site_type="active"
                     /db_xref="CDD:187559"
ORIGIN      
        1 miivtggagf igsnivkaln dkgitdilvv dnlkdgtkfv nlvdlniady mdkedfliqi
       61 mageefgdve aifhegacss ttewdgkymm dnnyqyskel lhyclereip flyassaaty
      121 ggrtsdfies reyekplnvy gyskflfdey vrqilpeans qivgfryfnv ygpreghkgs
      181 masvafhlnt qlnngespkl fegsenfkrd fvyvgdvadv nlwflengvs gifnlgtgra
      241 esfqavadat layhkkgqie yipfpdklkg ryqaftqadl tnlraagydk pfktvaegvt
      301 eymawlnrda