MULTISPECIES: NADP(H)-dependent aldo-keto reductase [Salmonella].

LOCUS       WP_000558962             346 aa            linear   BCT 10-SEP-2020
ACCESSION   WP_000558962
VERSION     WP_000558962.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 346)
  AUTHORS   Obmolova,G., Teplyakov,A., Khil,P.P., Howard,A.J.,
            Camerini-Otero,R.D. and Gilliland,G.L.
  TITLE     Crystal structure of the Escherichia coli Tas protein, an
            NADP(H)-dependent aldo-keto reductase
  JOURNAL   Proteins 53 (2), 323-325 (2003)
   PUBMED   14517983
REFERENCE   2  (residues 1 to 346)
  AUTHORS   Johnson,J.M. 3rd, Ding,W., Henkhaus,J. and Fix,D.
  TITLE     Identification of a mutation causing increased expression of the
            tas gene in Escherichia coli FX-11
  JOURNAL   Mutat. Res. 479 (1-2), 121-130 (2001)
   PUBMED   11470487
REFERENCE   3  (residues 1 to 346)
  AUTHORS   Timms,A.R. and Bridges,B.A.
  TITLE     Reversion of the tyrosine ochre strain Escherichia coli WU3610
            under starvation conditions depends on a new gene tas
  JOURNAL   Genetics 148 (4), 1627-1635 (1998)
   PUBMED   9560382
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007912.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10625
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..346
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..346
                     /product="NADP(H)-dependent aldo-keto reductase"
                     /GO_function="GO:0047834 - D-threo-aldose 1-dehydrogenase
                     activity [Evidence IEA]"
                     /calculated_mol_wt=38433
     Region          1..346
                     /region_name="tas"
                     /note="putative aldo-keto reductase; Provisional;
                     PRK10625"
                     /db_xref="CDD:236727"
     Site            order(19..21,26,48,53,87,132,179..180,205,233..239,242,
                     244,253..255,289,306..310,314,318)
                     /site_type="active"
                     /db_xref="CDD:381320"
     Site            order(48,53,87,132)
                     /site_type="active"
                     /note="catalytic tetrad [active]"
                     /db_xref="CDD:381320"
ORIGIN      
        1 mhyhriphss levstlglgt mtfgeqnsea dahaqldyai anginlidaa emypvpprpe
       61 tqgltesyig nwlakrgnre kliiaskvsg parnndqgir phqaldrkni realhdsltr
      121 lqtdyldlyq vhwpqrptnc fgklgynwtd stpvvsllet ldalsefqra gkiryigvsn
      181 etafgvmryl hlaekhdlpr ivtiqnpysl lnrsyevgla evsqyegvel laysclafgt
      241 ltgkylngak pagarntlfs rftrysgeqa qkavasyvdi akrhnldpaq malafvrrqp
      301 fvastllgat tmaqlktnve slhltlseev laeieaahqv ytypap