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MULTISPECIES: 5-methylcytosine-specific endonuclease McrA


LOCUS       WP_000557907             277 aa            linear   BCT 24-FEB-2020
            [Enterobacteriaceae].
ACCESSION   WP_000557907
VERSION     WP_000557907.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 277)
  AUTHORS   Mulligan,E.A., Hatchwell,E., McCorkle,S.R. and Dunn,J.J.
  TITLE     Differential binding of Escherichia coli McrA protein to DNA
            sequences that contain the dinucleotide m5CpG
  JOURNAL   Nucleic Acids Res. 38 (6), 1997-2005 (2010)
   PUBMED   20015968
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011220
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..277
                     /gene="mcrA"
     Protein         1..277
                     /product="5-methylcytosine-specific endonuclease McrA"
                     /EC_number="3.1.21.-"
                     /calculated_mol_wt=31259
     Region          169..277
                     /region_name="COG3183"
                     /note="Predicted restriction endonuclease, HNH family
                     [Defense mechanisms]"
                     /db_xref="CDD:442416"
ORIGIN      
        1 mhvfdnngie lkaecsigee dgvygliles wgpgdrnkdy nialdyiier lvdsgvsqvv
       61 vylasssvrk hmhslderki hpgeyftlig nsprdirlkm cgyqayfsrt grkeipsgnr
      121 tkrilinvpg iysdsfwasi irgelselsq ptddesllnm rvsklikktl sqpegsrkpv
      181 everlqkvyv rdpmvkawil qqskgicenc gknapfylnd gnpylevhhv iplssggadt
      241 tdncvalcpn chrelhyskn akeliemlyv ninrlqk