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MULTISPECIES: toxin-antitoxin system antitoxin VapB [Bacteria].


LOCUS       WP_000557549              75 aa            linear   BCT 06-AUG-2024
ACCESSION   WP_000557549
VERSION     WP_000557549.1
KEYWORDS    RefSeq.
SOURCE      Bacteria (eubacteria)
  ORGANISM  Bacteria
            Unclassified.
REFERENCE   1  (residues 1 to 75)
  AUTHORS   Dienemann,C., Boggild,A., Winther,K.S., Gerdes,K. and
            Brodersen,D.E.
  TITLE     Crystal structure of the VapBC toxin-antitoxin complex from
            Shigella flexneri reveals a hetero-octameric DNA-binding assembly
  JOURNAL   J. Mol. Biol. 414 (5), 713-722 (2011)
   PUBMED   22037005
REFERENCE   2  (residues 1 to 75)
  AUTHORS   Winther,K.S. and Gerdes,K.
  TITLE     Enteric virulence associated protein VapC inhibits translation by
            cleavage of initiator tRNA
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 108 (18), 7403-7407 (2011)
   PUBMED   21502523
REFERENCE   3  (residues 1 to 75)
  AUTHORS   Winther,K.S. and Gerdes,K.
  TITLE     Ectopic production of VapCs from Enterobacteria inhibits
            translation and trans-activates YoeB mRNA interferase
  JOURNAL   Mol. Microbiol. 72 (4), 918-930 (2009)
   PUBMED   19400780
REFERENCE   4  (residues 1 to 75)
  AUTHORS   Radnedge,L., Davis,M.A., Youngren,B. and Austin,S.J.
  TITLE     Plasmid maintenance functions of the large virulence plasmid of
            Shigella flexneri
  JOURNAL   J. Bacteriol. 179 (11), 3670-3675 (1997)
   PUBMED   9171415
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR000828
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..75
                     /organism="Bacteria"
                     /db_xref="taxon:2"
     gene            1..75
                     /gene="vapB"
     Protein         1..75
                     /product="toxin-antitoxin system antitoxin VapB"
                     /calculated_mol_wt=8383
     Region          3..75
                     /region_name="TA_anti_VapB"
                     /note="type II toxin-antitoxin system VapB family
                     antitoxin; NF040493"
                     /db_xref="CDD:439718"
ORIGIN      
        1 mhttlffsnr tqavrlpksi sfpedvkhve iiavgrsrii tpvgeswdsw fdgegastdf
       61 mstreqpavq eregf