MULTISPECIES: voltage-gated ClC-type chloride channel ClcB

LOCUS       WP_000554911             429 aa            linear   BCT 03-JUN-2019
            [Salmonella].
ACCESSION   WP_000554911
VERSION     WP_000554911.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF002437.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK01610
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..429
                     /gene="clcB"
     Protein         1..429
                     /product="voltage-gated ClC-type chloride channel ClcB"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA]"
                     /GO_process="GO:0006821 - chloride transport [Evidence
                     IEA]"
                     /GO_process="GO:0010447 - response to acidic pH [Evidence
                     IEA]"
                     /calculated_mol_wt=45450
     Region          13..429
                     /region_name="PRK01610"
                     /note="putative voltage-gated ClC-type chloride channel
                     ClcB; Provisional"
                     /db_xref="CDD:234963"
     Site            order(96..100,130..134,332..336)
                     /site_type="active"
                     /note="Cl- selectivity filter [active]"
                     /db_xref="CDD:238233"
     Site            order(97,99,132..133,332..334)
                     /site_type="other"
                     /note="Cl- binding residues [ion binding]"
                     /db_xref="CDD:238233"
     Site            132
                     /site_type="active"
                     /note="pore gating glutamate residue [active]"
                     /db_xref="CDD:238233"
     Site            order(176,185,200,207,380,383,391,399,406..407)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238233"
ORIGIN      
        1 mhrlhaypdl ramfrrllia tligilaala vaafrhamql lewiflsndt gslvnaaegl
       61 spwrrlitpa lgglaaglll wgwqkmnqqr phaptdymea lqtdgqfdvg aslvkslasl
      121 lvvvsgsaig regamillaa laassfarrf tpreewklwi asgaaagmag ayhaplagsl
      181 fiaeilfgtl mlaslgpvvv savvalltth vlngsdslly tvhltvdlha reyvmivstg
      241 lvaglcgpll mwlmtashns flrlklsppw qlalgglivg llslltptvw gngysvvqsf
      301 llspplfsli ggifvckila vlassgsgap ggvftptlfv glsigmflgr iwgfwlpgsd
      361 eiaillglag matllaatth apimstlmic emtgeyqllp glliacvvas vlsrtlrhds
      421 iyrqhaaeh