medium-chain fatty-acid--CoA ligase [Escherichia coli].

LOCUS       WP_000553704             566 aa            linear   BCT 13-MAR-2021
ACCESSION   WP_000553704
VERSION     WP_000553704.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF004758.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK06087
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..566
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..566
                     /gene="fadK"
     Protein         1..566
                     /product="medium-chain fatty-acid--CoA ligase"
                     /EC_number="6.2.1.-"
                     /calculated_mol_wt=62629
     Region          20..566
                     /region_name="PRK06087"
                     /note="medium-chain fatty-acid--CoA ligase"
                     /db_xref="CDD:180393"
     Site            order(211,214..219,221..222)
                     /site_type="other"
                     /note="acyl-activating enzyme (AAE) consensus motif"
                     /db_xref="CDD:341229"
     Site            order(214,329..330,350..355,435,447,450,461,543)
                     /site_type="other"
                     /note="putative AMP binding site [chemical binding]"
                     /db_xref="CDD:341229"
     Site            order(214,254..255,302,304..305,308,329..330,350..355,435,
                     447,450,458..461,524)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:341229"
     Site            order(254,304..305,308,329,458..460,517,524)
                     /site_type="other"
                     /note="putative CoA binding site [chemical binding]"
                     /db_xref="CDD:341229"
ORIGIN      
        1 mhptgphlgp dvlfresnmk vtltfneqrr aayrqqglwg dasladywqq tarampdkia
       61 vvdnhgasyt ysaldhaasc lanwmlakgi esgdriafql pgwceftviy laclkigavs
      121 vpllpswrea elvwvlnkcq akmffaptlf kqtrpvdlil plqnqlpqlq qivgvdklap
      181 atsslslsqi iadntsltta itthgdelaa vlftsgtegl pkgvmlthnn ilaserayca
      241 rlnltwqdvf mmpaplghat gflhgvtapf ligarsvlld iftpdaclal leqqrctcml
      301 gatpfvydll nvlekqpadl salrfflcgg ttipkkvare cqqrgiklls vygstessph
      361 avvnlddpls rfmhtdgyaa agveikvvdd arktlppgce geeasrgpnv fmgyfdepel
      421 taraldeegw yysgdlcrmd eagyikitgr kkdiivrgge nissrevedi llqhpkihda
      481 cvvamsderl gerscayvvl kaphhslsle evvaffsrkr vakykypehi vvieklprtt
      541 sgkiqkfllr kdimrrltqd vceeie