porphobilinogen synthase [Shigella flexneri].

LOCUS       WP_000550526             335 aa            linear   BCT 07-MAR-2020
ACCESSION   WP_000550526
VERSION     WP_000550526.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF009923.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK13384
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..335
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     gene            1..335
                     /gene="hemB"
     Protein         1..335
                     /product="porphobilinogen synthase"
                     /EC_number="4.2.1.24"
                     /GO_function="GO:0004655 - porphobilinogen synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0033014 - tetrapyrrole biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=36790
     Region          12..330
                     /region_name="PRK09283"
                     /note="porphobilinogen synthase"
                     /db_xref="CDD:236450"
     Site            order(20,23..24,35,59,62,151..152,179..180,209..211,230,
                     233,239,242..243,261..265,289,307,311,314)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238226"
     Site            order(129,131,133,141,176,206,212,215..216,221,227,231,
                     258,281,284,323)
                     /site_type="active"
                     /db_xref="CDD:238226"
     Site            order(206,258)
                     /site_type="active"
                     /note="Schiff base residues [active]"
                     /db_xref="CDD:238226"
ORIGIN      
        1 mhlnstnirq tmtdliqrpr rlrkspalra mfeettlsln dlvlpifvee eiddykavea
       61 mpgvmripek hlareieria nagirsvmtf gishhtdetg sdawredglv armsrickqt
      121 vpemivmsdt cfceytshgh cgvlcehgvd ndatlenlgk qavvaaaaga dfiapsaamd
      181 gqvqairqal daagfkdtai msystkfass fygpfreaag salkgdrksy qmnpmnrrea
      241 ireslldeaq gadclmvkpa gayldivrel rertelpiga yqvsgeyami kfaalagaid
      301 eekvvleslg sikragadli fsyfaldlae kkilr