Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: 4-hydroxy-tetrahydrodipicolinate reductase


LOCUS       WP_000544031             273 aa            linear   BCT 29-APR-2021
            [Salmonella].
ACCESSION   WP_000544031
VERSION     WP_000544031.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 273)
  AUTHORS   Scapin,G., Reddy,S.G., Zheng,R. and Blanchard,J.S.
  TITLE     Three-dimensional structure of Escherichia coli dihydrodipicolinate
            reductase in complex with NADH and the inhibitor
            2,6-pyridinedicarboxylate
  JOURNAL   Biochemistry 36 (49), 15081-15088 (1997)
   PUBMED   9398235
REFERENCE   2  (residues 1 to 273)
  AUTHORS   Pavelka,M.S. Jr., Weisbrod,T.R. and Jacobs,W.R. Jr.
  TITLE     Cloning of the dapB gene, encoding dihydrodipicolinate reductase,
            from Mycobacterium tuberculosis
  JOURNAL   J Bacteriol 179 (8), 2777-2782 (1997)
   PUBMED   9098082
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00036.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..273
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..273
                     /gene="dapB"
     Protein         1..273
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /EC_number="1.17.1.8"
                     /GO_function="GO:0008839 -
                     4-hydroxy-tetrahydrodipicolinate reductase [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /calculated_mol_wt=28720
     Region          6..268
                     /region_name="DapB"
                     /note="4-hydroxy-tetrahydrodipicolinate reductase [Amino
                     acid transport and metabolism]; COG0289"
                     /db_xref="CDD:440058"
ORIGIN      
        1 mheaqirvai agaggrmgrq liqaamameg vqlgaalere gssllgsdag elagagksgv
       61 ivqssleavk ddfdvfidft rpegtlthla fcrqhgkgmv igttgfddag kqaireasqe
      121 iaivfaanfs vgvnvmlkll ekaakvmgdy sdieiieahh rhkvdapsgt alamgeaiag
      181 aldknlkdca vysregytge rvagtigfat vragdivgeh tamfadiger veithkassr
      241 mtfangalrs alwlktkkng lfdmrdvlgl dvl